Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance

Repurposing Drugs for Synergistic Combination Therapies to Counteract Monkeypox Virus Tecovirimat Resistance

The ongoing monkeypox (mpox) disease outbreak has spread to multiple countries in Central Africa and evidence indicates it is driven by a more virulent clade I monkeypox virus (MPXV) strain than the clade II strain associated with the 2022 global mpox outbreak, which led the WHO to declare this mpox...

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Bibliographic Details
Main Authors: Haydar Witwit, Beatrice Cubitt, Roaa Khafaji, Esteban M. Castro, Miguel Goicoechea, Maria M. Lorenzo, Rafael Blasco, Luis Martinez-Sobrido, Juan C. de la Torre
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Viruses
Subjects:
monkeypox
antiviral
mpox
drug synergistic interactions
<i>Poxviridae</i>
VACV
Online Access:https://www.mdpi.com/1999-4915/17/1/92
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