Bioinformatics analysis reveals key mechanisms of oligodendrocytes and oligodendrocyte precursor cells regulation in spinal cord Injury

Bioinformatics analysis reveals key mechanisms of oligodendrocytes and oligodendrocyte precursor cells regulation in spinal cord Injury

Abstract Despite extensive research, spinal cord injuries (SCI), which could cause severe sensory, motor and autonomic dysfunction, remain largely incurable. Oligodendrocytes and oligodendrocyte precursor cells (ODC/OPC) play a crucial role in neural morphological repair and functional recovery foll...

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Bibliographic Details
Main Authors: Xi Yue, Xunling Chen, Yang Zang, Jinliang Wu, Guanhao Chen, Hongyu Tan, Kerong Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Spinal cord injury
ODC/OPC
Multi-omics
Regulatory network
Potential drugs
Online Access:https://doi.org/10.1038/s41598-025-90489-z
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