Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives

<strong>Foundation:</strong> diabetes mellitus is one of the diseases with the highest morbidity and mortality among non-communicable chronic conditions and its prevalence in individuals with a first-degree family history is high. <br /><strong>Objective:</strong> to de...

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Main Authors: María Teresa González Pedroso, Elizabeth Remis Rodríguez, Marlene Ferrer Arrocha, Marisela Nuez Villar, Ingrid Rodríguez Crespo, Héctor Pérez Assef
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2023-05-01
Series:Revista Finlay
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Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/1222
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author María Teresa González Pedroso
Elizabeth Remis Rodríguez
Marlene Ferrer Arrocha
Marisela Nuez Villar
Ingrid Rodríguez Crespo
Héctor Pérez Assef
author_facet María Teresa González Pedroso
Elizabeth Remis Rodríguez
Marlene Ferrer Arrocha
Marisela Nuez Villar
Ingrid Rodríguez Crespo
Héctor Pérez Assef
author_sort María Teresa González Pedroso
collection DOAJ
description <strong>Foundation:</strong> diabetes mellitus is one of the diseases with the highest morbidity and mortality among non-communicable chronic conditions and its prevalence in individuals with a first-degree family history is high. <br /><strong>Objective:</strong> to describe the alterations in glucose metabolism and the atherogenic risk factors present in diabetic patients’ first-degree relatives of a medical office. <br /><strong>Method:</strong> a descriptive cross-sectional study was carried out between January 2020 and January 2022, which included first-degree relatives of type 2 diabetic patients, dispensed at medical office No. 10 belonging to the Héroes del Moncada University Policlinic from the Plaza de la Revolución municipality, 122 patients older than 19 years old were studied. The following variables were analyzed: age, sex, and skin color, atherogenic risk factors, and changes in carbohydrate metabolism. <br /><strong>Results:</strong> female patients and the age group 19 and 39 years old predominated. The most frequent risk factor was dyslipidemia, present in 43,4 % followed by arterial hypertension and overweight/obesity. Alterations in glucose metabolism occurred in 74,6 % of the patients, with a predominance of altered fasting glycemia in 30,3 % and 11,5 % diagnosed with diabetes mellitus. <br /><strong>Conclusions:</strong> the alterations in glucose metabolism and the atherogenic risk factors detected reveal the association between genetic and environmental factors in the development of the disease and the importance of developing prevention strategies from an early age of life.
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spelling doaj-art-d8a820a4467d4cacac6b1b1ec8dde84b2025-01-30T21:22:02ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342023-05-01132136143631Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree RelativesMaría Teresa González Pedroso0Elizabeth Remis Rodríguez1Marlene Ferrer Arrocha2Marisela Nuez Villar3Ingrid Rodríguez Crespo4Héctor Pérez Assef5Policlínico Docente Héroes de Girón. La Habana.Policlínico Docente Héroes de Girón. La Habana.Centro de Investigaciones y Referencias de Aterosclerosis. La Habana.Hospital Clínico Quirúrgico Hermanos Ameijeiras. La Habana.Policlínico Docente Héroes de Girón. La Habana.Hospital Clínico Quirúrgico Hermanos Ameijeiras. La Habana.<strong>Foundation:</strong> diabetes mellitus is one of the diseases with the highest morbidity and mortality among non-communicable chronic conditions and its prevalence in individuals with a first-degree family history is high. <br /><strong>Objective:</strong> to describe the alterations in glucose metabolism and the atherogenic risk factors present in diabetic patients’ first-degree relatives of a medical office. <br /><strong>Method:</strong> a descriptive cross-sectional study was carried out between January 2020 and January 2022, which included first-degree relatives of type 2 diabetic patients, dispensed at medical office No. 10 belonging to the Héroes del Moncada University Policlinic from the Plaza de la Revolución municipality, 122 patients older than 19 years old were studied. The following variables were analyzed: age, sex, and skin color, atherogenic risk factors, and changes in carbohydrate metabolism. <br /><strong>Results:</strong> female patients and the age group 19 and 39 years old predominated. The most frequent risk factor was dyslipidemia, present in 43,4 % followed by arterial hypertension and overweight/obesity. Alterations in glucose metabolism occurred in 74,6 % of the patients, with a predominance of altered fasting glycemia in 30,3 % and 11,5 % diagnosed with diabetes mellitus. <br /><strong>Conclusions:</strong> the alterations in glucose metabolism and the atherogenic risk factors detected reveal the association between genetic and environmental factors in the development of the disease and the importance of developing prevention strategies from an early age of life.https://revfinlay.sld.cu/index.php/finlay/article/view/1222factores de riesgodiabetes mellituscomplicaciones de la diabetes
spellingShingle María Teresa González Pedroso
Elizabeth Remis Rodríguez
Marlene Ferrer Arrocha
Marisela Nuez Villar
Ingrid Rodríguez Crespo
Héctor Pérez Assef
Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives
Revista Finlay
factores de riesgo
diabetes mellitus
complicaciones de la diabetes
title Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives
title_full Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives
title_fullStr Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives
title_full_unstemmed Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives
title_short Changes in Glucose Metabolism and Atherogenic Risk Factors in Diabetic Patients’ First-degree Relatives
title_sort changes in glucose metabolism and atherogenic risk factors in diabetic patients first degree relatives
topic factores de riesgo
diabetes mellitus
complicaciones de la diabetes
url https://revfinlay.sld.cu/index.php/finlay/article/view/1222
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