Methadone-Induced Toxic Brain Damage

A 29-year-old man presented with comatose after methadone intoxication. Cerebral tomography only showed cortico-subcortical hypodense signal in the right cerebellar hemisphere. Brain MRI showed a rare imaging of FLAIR and DWI hyperintensities in the two cerebellar hemispheres as well as basal gangli...

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Bibliographic Details
Main Authors: Jérôme Corré, Jérôme Pillot, Gilles Hilbert
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Radiology
Online Access:http://dx.doi.org/10.1155/2013/602981
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Summary:A 29-year-old man presented with comatose after methadone intoxication. Cerebral tomography only showed cortico-subcortical hypodense signal in the right cerebellar hemisphere. Brain MRI showed a rare imaging of FLAIR and DWI hyperintensities in the two cerebellar hemispheres as well as basal ganglia (globi pallidi), compatible with methadone overdose. To our knowledge this is the first reported case of both cerebellar and basal ganglia involvement in methadone overdose.
ISSN:2090-6862
2090-6870