Salivary Fluoride Levels after Use of High-Fluoride Dentifrice

The aim of the study was to evaluate salivary fluoride (F) availability after toothbrushing with a high-F dentifrice. Twelve adult volunteers took part in this crossover and blind study. F concentration in saliva was determined after brushing with a high-F dentifrice (5000 µg F/g) or with a conventi...

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Main Authors: Glauber Campos Vale, Priscila Figueiredo Cruz, Ana Clarissa Cavalcante Elvas Bohn, Marcoeli Silva de Moura
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1155/2015/302717
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author Glauber Campos Vale
Priscila Figueiredo Cruz
Ana Clarissa Cavalcante Elvas Bohn
Marcoeli Silva de Moura
author_facet Glauber Campos Vale
Priscila Figueiredo Cruz
Ana Clarissa Cavalcante Elvas Bohn
Marcoeli Silva de Moura
author_sort Glauber Campos Vale
collection DOAJ
description The aim of the study was to evaluate salivary fluoride (F) availability after toothbrushing with a high-F dentifrice. Twelve adult volunteers took part in this crossover and blind study. F concentration in saliva was determined after brushing with a high-F dentifrice (5000 µg F/g) or with a conventional F concentration dentifrice (1100 µg F/g) followed by a 15 mL distilled water rinse. Samples of nonstimulated saliva were collected on the following times: before (baseline), and immediately after spit (time = 0) and after 1, 2, 3, 4, 5, 10, 15, 20, 30, 45, 60, 90, and 120 min. F analysis was performed with a fluoride-sensitive electrode and the area under curve of F salivary concentration × time (µg F/mL × min−1) was calculated. At baseline, no significant difference was found among dentifrices (P > 0.05). After brushing, both dentifrices caused an elevated fluoride level in saliva; however salivary F concentration was significantly higher at all times, when high-F dentifrice was used (P < 0.01). Even after 120 min, salivary F concentration was still higher than the baseline values for both dentifrices (P < 0.001). High-F dentifrice enhanced the bioavailability of salivary F, being an option for caries management in patients with high caries risk.
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institution Kabale University
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publishDate 2015-01-01
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series The Scientific World Journal
spelling doaj-art-d898341089bd4ef38c2f5fc664abeceb2025-02-03T01:28:05ZengWileyThe Scientific World Journal2356-61401537-744X2015-01-01201510.1155/2015/302717302717Salivary Fluoride Levels after Use of High-Fluoride DentifriceGlauber Campos Vale0Priscila Figueiredo Cruz1Ana Clarissa Cavalcante Elvas Bohn2Marcoeli Silva de Moura3Federal University of Piauí, 6404-550 Teresina, PI, BrazilFederal University of Piauí, 6404-550 Teresina, PI, BrazilFederal University of Piauí, 6404-550 Teresina, PI, BrazilFederal University of Piauí, 6404-550 Teresina, PI, BrazilThe aim of the study was to evaluate salivary fluoride (F) availability after toothbrushing with a high-F dentifrice. Twelve adult volunteers took part in this crossover and blind study. F concentration in saliva was determined after brushing with a high-F dentifrice (5000 µg F/g) or with a conventional F concentration dentifrice (1100 µg F/g) followed by a 15 mL distilled water rinse. Samples of nonstimulated saliva were collected on the following times: before (baseline), and immediately after spit (time = 0) and after 1, 2, 3, 4, 5, 10, 15, 20, 30, 45, 60, 90, and 120 min. F analysis was performed with a fluoride-sensitive electrode and the area under curve of F salivary concentration × time (µg F/mL × min−1) was calculated. At baseline, no significant difference was found among dentifrices (P > 0.05). After brushing, both dentifrices caused an elevated fluoride level in saliva; however salivary F concentration was significantly higher at all times, when high-F dentifrice was used (P < 0.01). Even after 120 min, salivary F concentration was still higher than the baseline values for both dentifrices (P < 0.001). High-F dentifrice enhanced the bioavailability of salivary F, being an option for caries management in patients with high caries risk.http://dx.doi.org/10.1155/2015/302717
spellingShingle Glauber Campos Vale
Priscila Figueiredo Cruz
Ana Clarissa Cavalcante Elvas Bohn
Marcoeli Silva de Moura
Salivary Fluoride Levels after Use of High-Fluoride Dentifrice
The Scientific World Journal
title Salivary Fluoride Levels after Use of High-Fluoride Dentifrice
title_full Salivary Fluoride Levels after Use of High-Fluoride Dentifrice
title_fullStr Salivary Fluoride Levels after Use of High-Fluoride Dentifrice
title_full_unstemmed Salivary Fluoride Levels after Use of High-Fluoride Dentifrice
title_short Salivary Fluoride Levels after Use of High-Fluoride Dentifrice
title_sort salivary fluoride levels after use of high fluoride dentifrice
url http://dx.doi.org/10.1155/2015/302717
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AT anaclarissacavalcanteelvasbohn salivaryfluoridelevelsafteruseofhighfluoridedentifrice
AT marcoelisilvademoura salivaryfluoridelevelsafteruseofhighfluoridedentifrice