In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta
Homalomena occulta, a plant widely used in traditional Vietnamese medicine, was assessed for its antioxidant potential through DPPH radical scavenging and total antioxidant capacity methods. The results showed that Homalomena occulta exhibited significant antioxidant activities with a low IC50 valu...
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HUJOS
2024-06-01
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| Series: | Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên |
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| Online Access: | https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/7256 |
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| author | Trang Le Thuy Son Le Lam Dung Nguyen Van Anh Vu Ho Xuan Man Nguyen Quang Minh Tran Thanh Thi Tran Thi Van Thang Nguyen Viet Ly Vo Thi Khanh Nhung Nguyen Minh Hieu Le Trung |
| author_facet | Trang Le Thuy Son Le Lam Dung Nguyen Van Anh Vu Ho Xuan Man Nguyen Quang Minh Tran Thanh Thi Tran Thi Van Thang Nguyen Viet Ly Vo Thi Khanh Nhung Nguyen Minh Hieu Le Trung |
| author_sort | Trang Le Thuy |
| collection | DOAJ |
| description |
Homalomena occulta, a plant widely used in traditional Vietnamese medicine, was assessed for its antioxidant potential through DPPH radical scavenging and total antioxidant capacity methods. The results showed that Homalomena occulta exhibited significant antioxidant activities with a low IC50 value of 40.27 μg/mL, which is comparable to that of curcumin (38.50 μg/mL). Furthermore, the total antioxidant capacity of the Homalomena occulta extract was determined to be 77.48 ± 2.34 mg GA/g. To investigate the composition of the plant, various compounds including total phenolic, total flavonoid, polysaccharides, and triterpenoids were quantified using colorimetric methods with specific reagents. The content of phenolic compounds, flavonoid compounds, polysaccharides, and triterpenoids in Homalomena occulta was found to be 36.87 ± 0.42 GAE/g, 26.83 ± 0.29 mg QUE/g, 5.06 ± 0.06%, and 52.09 ± 1.77 mg Olenanoic/g, respectively. Notably, this study provides the first-ever report on the polysaccharide and total triterpenoid content of Homalomena occulta.
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| format | Article |
| id | doaj-art-d88736be5c314667a6bec5b8f33dc615 |
| institution | Kabale University |
| issn | 1859-1388 2615-9678 |
| language | English |
| publishDate | 2024-06-01 |
| publisher | HUJOS |
| record_format | Article |
| series | Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên |
| spelling | doaj-art-d88736be5c314667a6bec5b8f33dc6152025-02-03T01:56:51ZengHUJOSTạp chí Khoa học Đại học Huế: Khoa học Tự nhiên1859-13882615-96782024-06-011331B10.26459/hueunijns.v133i1B.7256In vitro antioxidant activity and content of bioactive compounds from Homalomena occultaTrang Le Thuy0Son Le Lam1Dung Nguyen Van2Anh Vu Ho Xuan3Man Nguyen Quang4Minh Tran Thanh5Thi Tran Thi Van6Thang Nguyen Viet7Ly Vo Thi Khanh8Nhung Nguyen Minh9Hieu Le Trung10University of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamDak Mil High School, Dak Mil, Dak Nong, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamUniversity of Medicine and Pharmacy, Hue University, 6 Ngo Quyen St., Hue, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamHue Medical College, 01 Nguyen Truong To St., Hue, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet NamUniversity of Sciences, Hue University, 77 Nguyen Hue St., Hue, Viet Nam Homalomena occulta, a plant widely used in traditional Vietnamese medicine, was assessed for its antioxidant potential through DPPH radical scavenging and total antioxidant capacity methods. The results showed that Homalomena occulta exhibited significant antioxidant activities with a low IC50 value of 40.27 μg/mL, which is comparable to that of curcumin (38.50 μg/mL). Furthermore, the total antioxidant capacity of the Homalomena occulta extract was determined to be 77.48 ± 2.34 mg GA/g. To investigate the composition of the plant, various compounds including total phenolic, total flavonoid, polysaccharides, and triterpenoids were quantified using colorimetric methods with specific reagents. The content of phenolic compounds, flavonoid compounds, polysaccharides, and triterpenoids in Homalomena occulta was found to be 36.87 ± 0.42 GAE/g, 26.83 ± 0.29 mg QUE/g, 5.06 ± 0.06%, and 52.09 ± 1.77 mg Olenanoic/g, respectively. Notably, this study provides the first-ever report on the polysaccharide and total triterpenoid content of Homalomena occulta. https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/7256Homalomena occulta, antioxidant activity, polysaccharide, triterpenoids, total phenolic content, total flavonoid content. |
| spellingShingle | Trang Le Thuy Son Le Lam Dung Nguyen Van Anh Vu Ho Xuan Man Nguyen Quang Minh Tran Thanh Thi Tran Thi Van Thang Nguyen Viet Ly Vo Thi Khanh Nhung Nguyen Minh Hieu Le Trung In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên Homalomena occulta, antioxidant activity, polysaccharide, triterpenoids, total phenolic content, total flavonoid content. |
| title | In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta |
| title_full | In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta |
| title_fullStr | In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta |
| title_full_unstemmed | In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta |
| title_short | In vitro antioxidant activity and content of bioactive compounds from Homalomena occulta |
| title_sort | in vitro antioxidant activity and content of bioactive compounds from homalomena occulta |
| topic | Homalomena occulta, antioxidant activity, polysaccharide, triterpenoids, total phenolic content, total flavonoid content. |
| url | https://jos.hueuni.edu.vn/index.php/hujos-ns/article/view/7256 |
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