Recurrent Giant Malignant Phyllodes Tumor of the Breast

Phyllodes tumors (PTs) are rare fibroepithelial neoplasms of the breast. They have a proliferating stromal component that can be graded as benign, borderline, and malignant. In addition, they are associated with an increased risk of local recurrence and distant metastasis. The authors hereby present...

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Main Authors: Erik Kudela, Karol Kajo, Erik Kozubik, Tomas Rokos, Terezia Pribulova, Jan Danko, Eva Kudelova, Igor Homola, Pavol Slavik, Barbora Macurova, Kamil Biringer
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2021/2476691
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author Erik Kudela
Karol Kajo
Erik Kozubik
Tomas Rokos
Terezia Pribulova
Jan Danko
Eva Kudelova
Igor Homola
Pavol Slavik
Barbora Macurova
Kamil Biringer
author_facet Erik Kudela
Karol Kajo
Erik Kozubik
Tomas Rokos
Terezia Pribulova
Jan Danko
Eva Kudelova
Igor Homola
Pavol Slavik
Barbora Macurova
Kamil Biringer
author_sort Erik Kudela
collection DOAJ
description Phyllodes tumors (PTs) are rare fibroepithelial neoplasms of the breast. They have a proliferating stromal component that can be graded as benign, borderline, and malignant. In addition, they are associated with an increased risk of local recurrence and distant metastasis. The authors hereby present a case report of a 34-year-old woman with recurrent malignant PT with an increasing aggressiveness. There were two recurrences of giant tumors that consumed the entire right breast, which developed over a three-year period. The final surgical treatment was a total extirpation of the tumor with subsequent plastic reconstruction using a cutaneous flap from the region of the latissimus dorsi muscle. The patient died three months after the last recurrence due to multiorgan failure.
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issn 2090-6684
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publishDate 2021-01-01
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-d8625fe3564e4b08a9a6acae0049af862025-02-03T01:27:24ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922021-01-01202110.1155/2021/24766912476691Recurrent Giant Malignant Phyllodes Tumor of the BreastErik Kudela0Karol Kajo1Erik Kozubik2Tomas Rokos3Terezia Pribulova4Jan Danko5Eva Kudelova6Igor Homola7Pavol Slavik8Barbora Macurova9Kamil Biringer10Department of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaDepartment of Pathology, St. Elisabeth Cancer Institute, 812 50 Bratislava, SlovakiaDepartment of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaDepartment of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaDepartment of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaDepartment of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaClinic of Surgery and Transplant Center, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaDepartment of Plastic Surgery, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaInstitute of Pathological Anatomy, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaClinic of Radiology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaDepartment of Obstetrics & Gynecology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, SlovakiaPhyllodes tumors (PTs) are rare fibroepithelial neoplasms of the breast. They have a proliferating stromal component that can be graded as benign, borderline, and malignant. In addition, they are associated with an increased risk of local recurrence and distant metastasis. The authors hereby present a case report of a 34-year-old woman with recurrent malignant PT with an increasing aggressiveness. There were two recurrences of giant tumors that consumed the entire right breast, which developed over a three-year period. The final surgical treatment was a total extirpation of the tumor with subsequent plastic reconstruction using a cutaneous flap from the region of the latissimus dorsi muscle. The patient died three months after the last recurrence due to multiorgan failure.http://dx.doi.org/10.1155/2021/2476691
spellingShingle Erik Kudela
Karol Kajo
Erik Kozubik
Tomas Rokos
Terezia Pribulova
Jan Danko
Eva Kudelova
Igor Homola
Pavol Slavik
Barbora Macurova
Kamil Biringer
Recurrent Giant Malignant Phyllodes Tumor of the Breast
Case Reports in Obstetrics and Gynecology
title Recurrent Giant Malignant Phyllodes Tumor of the Breast
title_full Recurrent Giant Malignant Phyllodes Tumor of the Breast
title_fullStr Recurrent Giant Malignant Phyllodes Tumor of the Breast
title_full_unstemmed Recurrent Giant Malignant Phyllodes Tumor of the Breast
title_short Recurrent Giant Malignant Phyllodes Tumor of the Breast
title_sort recurrent giant malignant phyllodes tumor of the breast
url http://dx.doi.org/10.1155/2021/2476691
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