Proteomics and Its Current Application in Biomedical Area: Concise Review
Biomedical researchers tirelessly seek cutting-edge technologies to advance disease diagnosis, drug discovery, and therapeutic interventions, all aimed at enhancing human and animal well-being. Within this realm, proteomics stands out as a pivotal technology, focusing on extensive studies of protein...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2024/4454744 |
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| _version_ | 1832546165010202624 |
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| author | Semira Gobena Bemrew Admassu Mebrie Zemene Kinde Abebe Tesfaye Gessese |
| author_facet | Semira Gobena Bemrew Admassu Mebrie Zemene Kinde Abebe Tesfaye Gessese |
| author_sort | Semira Gobena |
| collection | DOAJ |
| description | Biomedical researchers tirelessly seek cutting-edge technologies to advance disease diagnosis, drug discovery, and therapeutic interventions, all aimed at enhancing human and animal well-being. Within this realm, proteomics stands out as a pivotal technology, focusing on extensive studies of protein composition, structure, function, and interactions. Proteomics, with its subdivisions of expression, structural, and functional proteomics, plays a crucial role in unraveling the complexities of biological systems. Various sophisticated techniques are employed in proteomics, including polyacrylamide gel electrophoresis, mass spectrometry analysis, NMR spectroscopy, protein microarray, X-ray crystallography, and Edman sequencing. These methods collectively contribute to the comprehensive understanding of proteins and their roles in health and disease. In the biomedical field, proteomics finds widespread application in cancer research and diagnosis, stem cell studies, and the diagnosis and research of both infectious and noninfectious diseases. In addition, it plays a pivotal role in drug discovery and the emerging frontier of personalized medicine. The versatility of proteomics allows researchers to delve into the intricacies of molecular mechanisms, paving the way for innovative therapeutic approaches. As infectious and noninfectious diseases continue to emerge and the field of biomedical research expands, the significance of proteomics becomes increasingly evident. Keeping abreast of the latest developments in proteomics applications becomes paramount for the development of therapeutics, translational research, and study of diverse diseases. This review aims to provide a comprehensive overview of proteomics, offering a concise outline of its current applications in the biomedical domain. By doing so, it seeks to contribute to the understanding and advancement of proteomics, emphasizing its pivotal role in shaping the future of biomedical research and therapeutic interventions. |
| format | Article |
| id | doaj-art-d82d82c0925e49b1930e25ccff2fc14f |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-d82d82c0925e49b1930e25ccff2fc14f2025-02-03T07:23:43ZengWileyThe Scientific World Journal1537-744X2024-01-01202410.1155/2024/4454744Proteomics and Its Current Application in Biomedical Area: Concise ReviewSemira Gobena0Bemrew Admassu1Mebrie Zemene Kinde2Abebe Tesfaye Gessese3College of Veterinary Medicine and Animal SciencesDepartment of Veterinary Biomedical SciencesDepartment of Veterinary Biomedical SciencesDepartment of Veterinary Biomedical SciencesBiomedical researchers tirelessly seek cutting-edge technologies to advance disease diagnosis, drug discovery, and therapeutic interventions, all aimed at enhancing human and animal well-being. Within this realm, proteomics stands out as a pivotal technology, focusing on extensive studies of protein composition, structure, function, and interactions. Proteomics, with its subdivisions of expression, structural, and functional proteomics, plays a crucial role in unraveling the complexities of biological systems. Various sophisticated techniques are employed in proteomics, including polyacrylamide gel electrophoresis, mass spectrometry analysis, NMR spectroscopy, protein microarray, X-ray crystallography, and Edman sequencing. These methods collectively contribute to the comprehensive understanding of proteins and their roles in health and disease. In the biomedical field, proteomics finds widespread application in cancer research and diagnosis, stem cell studies, and the diagnosis and research of both infectious and noninfectious diseases. In addition, it plays a pivotal role in drug discovery and the emerging frontier of personalized medicine. The versatility of proteomics allows researchers to delve into the intricacies of molecular mechanisms, paving the way for innovative therapeutic approaches. As infectious and noninfectious diseases continue to emerge and the field of biomedical research expands, the significance of proteomics becomes increasingly evident. Keeping abreast of the latest developments in proteomics applications becomes paramount for the development of therapeutics, translational research, and study of diverse diseases. This review aims to provide a comprehensive overview of proteomics, offering a concise outline of its current applications in the biomedical domain. By doing so, it seeks to contribute to the understanding and advancement of proteomics, emphasizing its pivotal role in shaping the future of biomedical research and therapeutic interventions.http://dx.doi.org/10.1155/2024/4454744 |
| spellingShingle | Semira Gobena Bemrew Admassu Mebrie Zemene Kinde Abebe Tesfaye Gessese Proteomics and Its Current Application in Biomedical Area: Concise Review The Scientific World Journal |
| title | Proteomics and Its Current Application in Biomedical Area: Concise Review |
| title_full | Proteomics and Its Current Application in Biomedical Area: Concise Review |
| title_fullStr | Proteomics and Its Current Application in Biomedical Area: Concise Review |
| title_full_unstemmed | Proteomics and Its Current Application in Biomedical Area: Concise Review |
| title_short | Proteomics and Its Current Application in Biomedical Area: Concise Review |
| title_sort | proteomics and its current application in biomedical area concise review |
| url | http://dx.doi.org/10.1155/2024/4454744 |
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