Metabonomics Research Progress on Liver Diseases

Metabolomics as the new omics technique develops after genomics, transcriptomics, and proteomics and has rapid development at present. Liver diseases are worldwide public health problems. In China, chronic hepatitis B and its secondary diseases are the common liver diseases. They can be diagnosed by...

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Main Authors: Mengqian Yu, Ying Zhu, Qingwei Cong, Chunyan Wu
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2017/8467192
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author Mengqian Yu
Ying Zhu
Qingwei Cong
Chunyan Wu
author_facet Mengqian Yu
Ying Zhu
Qingwei Cong
Chunyan Wu
author_sort Mengqian Yu
collection DOAJ
description Metabolomics as the new omics technique develops after genomics, transcriptomics, and proteomics and has rapid development at present. Liver diseases are worldwide public health problems. In China, chronic hepatitis B and its secondary diseases are the common liver diseases. They can be diagnosed by the combination of history, virology, liver function, and medical imaging. However, some patients seldom have relevant physical examination, so the diagnosis may be delayed. Many other liver diseases, such as drug-induced liver injury (DILI), alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), and autoimmune liver diseases, still do not have definite diagnostic markers; the diagnosis consists of history, medical imaging, and the relevant score. As a result, the clinical work becomes very complex. So it has broad prospects to explore the specific and sensitive biomarkers of liver diseases with metabolomics. In this paper, there are several summaries which are related to the current research progress and application of metabolomics on biomarkers of liver diseases.
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spelling doaj-art-d81e1535a2224e61bcd18aabfa2729872025-02-03T06:07:15ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972017-01-01201710.1155/2017/84671928467192Metabonomics Research Progress on Liver DiseasesMengqian Yu0Ying Zhu1Qingwei Cong2Chunyan Wu3Department of Infectious Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116000, ChinaDepartment of Infectious Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116000, ChinaDepartment of Infectious Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116000, ChinaDepartment of Infectious Diseases, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116000, ChinaMetabolomics as the new omics technique develops after genomics, transcriptomics, and proteomics and has rapid development at present. Liver diseases are worldwide public health problems. In China, chronic hepatitis B and its secondary diseases are the common liver diseases. They can be diagnosed by the combination of history, virology, liver function, and medical imaging. However, some patients seldom have relevant physical examination, so the diagnosis may be delayed. Many other liver diseases, such as drug-induced liver injury (DILI), alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD), and autoimmune liver diseases, still do not have definite diagnostic markers; the diagnosis consists of history, medical imaging, and the relevant score. As a result, the clinical work becomes very complex. So it has broad prospects to explore the specific and sensitive biomarkers of liver diseases with metabolomics. In this paper, there are several summaries which are related to the current research progress and application of metabolomics on biomarkers of liver diseases.http://dx.doi.org/10.1155/2017/8467192
spellingShingle Mengqian Yu
Ying Zhu
Qingwei Cong
Chunyan Wu
Metabonomics Research Progress on Liver Diseases
Canadian Journal of Gastroenterology and Hepatology
title Metabonomics Research Progress on Liver Diseases
title_full Metabonomics Research Progress on Liver Diseases
title_fullStr Metabonomics Research Progress on Liver Diseases
title_full_unstemmed Metabonomics Research Progress on Liver Diseases
title_short Metabonomics Research Progress on Liver Diseases
title_sort metabonomics research progress on liver diseases
url http://dx.doi.org/10.1155/2017/8467192
work_keys_str_mv AT mengqianyu metabonomicsresearchprogressonliverdiseases
AT yingzhu metabonomicsresearchprogressonliverdiseases
AT qingweicong metabonomicsresearchprogressonliverdiseases
AT chunyanwu metabonomicsresearchprogressonliverdiseases