Escherichia coli proteins uL29 and ACP stabilize the Tn7-encoded TnsD and its DNA binding

Escherichia coli proteins uL29 and ACP stabilize the Tn7-encoded TnsD and its DNA binding

Abstract Tn7 mobile genetic elements are known for their sophisticated target-site selection mechanisms and, in some cases, programmability. Recognition of target sites is mediated by designated transposon-encoded proteins and modulated by host factor proteins. In the case of the CRISPR-associated T...

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Bibliographic Details
Main Authors: Shani B. Leyva Camacho, Lindsay A. Matthews, Alba Guarné
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Mobile DNA
Subjects:
Tn7 transposition
Tn7 target-site selection
Host factors
Protein stability
Protein interactions
DNA-binding proteins
Online Access:https://doi.org/10.1186/s13100-025-00369-6
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