Study of polymorphisms in the interleukin-4 and IL-4 receptor genes in a population of Brazilian patients with multiple sclerosis Estudo de polimorfismos nos genes da interleucina-4 (*33C-T) e receptor IL-4 (*Q551R) numa população de pacientes brasileiros com esclerose múltipla

Study of polymorphisms in the interleukin-4 and IL-4 receptor genes in a population of Brazilian patients with multiple sclerosis Estudo de polimorfismos nos genes da interleucina-4 (*33C-T) e receptor IL-4 (*Q551R) numa população de pacientes brasileiros com esclerose múltipla

This study aimed to investigate in a population of Brazilian patients with multiple sclerosis (MS) single-nucleotide polymorphisms (SNP) in the promoter region of IL4 (*33C-T) and receptor IL4R (*Q551R A-G) genes proposed to interfere with disease progression. No significant differences were observe...

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Bibliographic Details
Main Authors: Thereza Quirico-Santos, Vijayaprakash Suppiah, Shirley Heggarty, Regina Caetano, Soniza Alves-Leon, Koen Vandenbroeck
Format: Article
Language:English
Published: Thieme Revinter Publicações 2007-03-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
esclerose múltipla
interleucina-4
receptor IL-4R
polimorfismo (SNP)
etnia
multiple sclerosis
interleukin-4
IL-4 receptor
single nucleotide polymorphism
ethnicity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2007000100005
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