Rhinoscleroma Causing Upper Airway Obstruction

Rhinoscleroma is a chronic granulomatous condition of the respiratory tract, and is not uncommon in tropical regions; particularly, Mexico, Central America and the Middle East. A few cases have been reported in North America, primarily involving immigrants from endemic countries. The causative organ...

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Main Authors: Geetika Verma, D Kanawaty, R Hyland
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2005/501457
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author Geetika Verma
D Kanawaty
R Hyland
author_facet Geetika Verma
D Kanawaty
R Hyland
author_sort Geetika Verma
collection DOAJ
description Rhinoscleroma is a chronic granulomatous condition of the respiratory tract, and is not uncommon in tropical regions; particularly, Mexico, Central America and the Middle East. A few cases have been reported in North America, primarily involving immigrants from endemic countries. The causative organism is Klebsiella rhinoscleromatis, a Gram-negative coccobacillus. Diagnosis is made on the basis of culture of the organism and the characteristic pathology of Mikulicz cells on light microscopy. The condition primarily affects the upper airway, and frequently presents with nasal discharge, nasal obstruction or frontal facial pain. Despite the term 'rhinoscleroma', there may be involvement of the entire respiratory tract. Although the condition is slowly progressive, its natural course portends extensive destruction. Laryngotracheal involvement occurs in approximately 15% to 80% of cases, but patients rarely present with isolated laryngotracheal disease. In the present paper, a case of rhinoscleroma presenting with symptoms of upper airway obstruction is described.
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spelling doaj-art-d7ab5936620f44e8bfe42d51dc940f862025-02-03T05:45:51ZengWileyCanadian Respiratory Journal1198-22412005-01-01121434510.1155/2005/501457Rhinoscleroma Causing Upper Airway ObstructionGeetika Verma0D Kanawaty1R Hyland2University of Toronto, Department of Medicine, CanadaUniversity of Toronto, Department of Medicine, CanadaUniversity of Toronto, Department of Medicine, CanadaRhinoscleroma is a chronic granulomatous condition of the respiratory tract, and is not uncommon in tropical regions; particularly, Mexico, Central America and the Middle East. A few cases have been reported in North America, primarily involving immigrants from endemic countries. The causative organism is Klebsiella rhinoscleromatis, a Gram-negative coccobacillus. Diagnosis is made on the basis of culture of the organism and the characteristic pathology of Mikulicz cells on light microscopy. The condition primarily affects the upper airway, and frequently presents with nasal discharge, nasal obstruction or frontal facial pain. Despite the term 'rhinoscleroma', there may be involvement of the entire respiratory tract. Although the condition is slowly progressive, its natural course portends extensive destruction. Laryngotracheal involvement occurs in approximately 15% to 80% of cases, but patients rarely present with isolated laryngotracheal disease. In the present paper, a case of rhinoscleroma presenting with symptoms of upper airway obstruction is described.http://dx.doi.org/10.1155/2005/501457
spellingShingle Geetika Verma
D Kanawaty
R Hyland
Rhinoscleroma Causing Upper Airway Obstruction
Canadian Respiratory Journal
title Rhinoscleroma Causing Upper Airway Obstruction
title_full Rhinoscleroma Causing Upper Airway Obstruction
title_fullStr Rhinoscleroma Causing Upper Airway Obstruction
title_full_unstemmed Rhinoscleroma Causing Upper Airway Obstruction
title_short Rhinoscleroma Causing Upper Airway Obstruction
title_sort rhinoscleroma causing upper airway obstruction
url http://dx.doi.org/10.1155/2005/501457
work_keys_str_mv AT geetikaverma rhinoscleromacausingupperairwayobstruction
AT dkanawaty rhinoscleromacausingupperairwayobstruction
AT rhyland rhinoscleromacausingupperairwayobstruction