T cell Activation Marker HLA-DR Reflects Tacrolimus-Associated Immunosuppressive Burden and BK Viremia Risk After Kidney Transplantation – An Observational Cohort Study

T cell Activation Marker HLA-DR Reflects Tacrolimus-Associated Immunosuppressive Burden and BK Viremia Risk After Kidney Transplantation – An Observational Cohort Study

Kidney transplantation (KT) is the current treatment of choice in patients with end-stage kidney disease. Immunosuppression is required to prevent acute rejection but is associated with a high incidence of adverse events. The immunosuppressive burden substantially differs between individuals, necess...

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Bibliographic Details
Main Authors: Simon Aberger, Max Schuller, Agnes A. Mooslechner, Konstantin A. Klötzer, Barbara Prietl, Verena Pfeifer, Alexander H. Kirsch, Alexander R. Rosenkranz, Katharina Artinger, Kathrin Eller
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Transplant International
Subjects:
immune monitoring
immunosuppression
kidney transplantation
translational nephrology
personalized medicine
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.14443/full
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