Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man

We report a case of a 60-year-old African American man who presented with a 4-year history of a previously asymptomatic, recently enlarging nodule on his left buttock, which was initially presumed to be an epidermoid cyst. Physical examination revealed a large, fixed, subcutaneous tumor, and a biops...

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Main Authors: Marissa J. Perman, Janelle M. King, Laurel L. Leithauser, Hugh M. Gloster
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2011/849767
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author Marissa J. Perman
Janelle M. King
Laurel L. Leithauser
Hugh M. Gloster
author_facet Marissa J. Perman
Janelle M. King
Laurel L. Leithauser
Hugh M. Gloster
author_sort Marissa J. Perman
collection DOAJ
description We report a case of a 60-year-old African American man who presented with a 4-year history of a previously asymptomatic, recently enlarging nodule on his left buttock, which was initially presumed to be an epidermoid cyst. Physical examination revealed a large, fixed, subcutaneous tumor, and a biopsy revealed merkel cell carcinoma. Immunohistochemical staining was positive for pankeratin, CAM 5.2, synaptophysin, and CD56 and negative for CK7, CK20, TTF-1, chromogranin, CD3, CD20, CD57, MART1, and HMB 45. The patient underwent wide local excision of the lesion with removal of the fascia overlying the gluteus and full body positron emission tomography (PET) and was found to have Stage IIb disease. He subsequently received adjuvant radiotherapy limited to the tumor bed at a dose of 60 gray.
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spelling doaj-art-d7960642656949df9e7e6a99800ec55d2025-02-03T01:24:06ZengWileyCase Reports in Oncological Medicine2090-67062090-67142011-01-01201110.1155/2011/849767849767Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American ManMarissa J. Perman0Janelle M. King1Laurel L. Leithauser2Hugh M. Gloster3Department of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USADepartment of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USADepartment of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USADepartment of Dermatology, College of Medicine, University of Cincinnati, Cincinnati, OH 45267, USAWe report a case of a 60-year-old African American man who presented with a 4-year history of a previously asymptomatic, recently enlarging nodule on his left buttock, which was initially presumed to be an epidermoid cyst. Physical examination revealed a large, fixed, subcutaneous tumor, and a biopsy revealed merkel cell carcinoma. Immunohistochemical staining was positive for pankeratin, CAM 5.2, synaptophysin, and CD56 and negative for CK7, CK20, TTF-1, chromogranin, CD3, CD20, CD57, MART1, and HMB 45. The patient underwent wide local excision of the lesion with removal of the fascia overlying the gluteus and full body positron emission tomography (PET) and was found to have Stage IIb disease. He subsequently received adjuvant radiotherapy limited to the tumor bed at a dose of 60 gray.http://dx.doi.org/10.1155/2011/849767
spellingShingle Marissa J. Perman
Janelle M. King
Laurel L. Leithauser
Hugh M. Gloster
Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man
Case Reports in Oncological Medicine
title Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man
title_full Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man
title_fullStr Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man
title_full_unstemmed Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man
title_short Giant Merkel Cell Carcinoma Masquerading as a Benign Cyst on the Buttock of an African American Man
title_sort giant merkel cell carcinoma masquerading as a benign cyst on the buttock of an african american man
url http://dx.doi.org/10.1155/2011/849767
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