Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus

Ionised active water S-100® has been proposed as an original solution for use in dermocosmetics and for the treatment of wounds such as burns and atopic dermatitis. Among the mechanisms of action that are not completely understood, an antimicrobial activity would appear to be important. In the conte...

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Main Authors: Nathalie Wurtz, Issam Hasni, Audrey Bancod, Bernard La Scola
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Advances in Virology
Online Access:http://dx.doi.org/10.1155/2022/5995775
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author Nathalie Wurtz
Issam Hasni
Audrey Bancod
Bernard La Scola
author_facet Nathalie Wurtz
Issam Hasni
Audrey Bancod
Bernard La Scola
author_sort Nathalie Wurtz
collection DOAJ
description Ionised active water S-100® has been proposed as an original solution for use in dermocosmetics and for the treatment of wounds such as burns and atopic dermatitis. Among the mechanisms of action that are not completely understood, an antimicrobial activity would appear to be important. In the context of the COVID-19 pandemic, we assessed the inactivating efficacy of this solution on SARS-CoV-2 based on the recommendations of the NF-EN-14476+A2 standard. The tests carried out demonstrated that ionised active water S-100® 40% has a virucidal activity on SARS-CoV-2 which is at least 3.1 log after a contact time of 30 seconds and 3.5 log after two minutes at 20°C under clean conditions. Assays were also performed at 4°C and 37°C, and the results obtained are identical to those obtained at 20°C. This demonstration of the virucidal effect of ionised water against SARS-CoV-2 paves the way for the development of usage as an alternative disinfectant in SARS-CoV-2 control.
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spelling doaj-art-d78da2bbb57f4b2e862b9a34a9221bd22025-02-03T01:23:09ZengWileyAdvances in Virology1687-86472022-01-01202210.1155/2022/5995775Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 VirusNathalie Wurtz0Issam Hasni1Audrey Bancod2Bernard La Scola3Aix Marseille UniversityInstitut Hospitalo-Universitaire Méditerranée-InfectionAix Marseille UniversityAix Marseille UniversityIonised active water S-100® has been proposed as an original solution for use in dermocosmetics and for the treatment of wounds such as burns and atopic dermatitis. Among the mechanisms of action that are not completely understood, an antimicrobial activity would appear to be important. In the context of the COVID-19 pandemic, we assessed the inactivating efficacy of this solution on SARS-CoV-2 based on the recommendations of the NF-EN-14476+A2 standard. The tests carried out demonstrated that ionised active water S-100® 40% has a virucidal activity on SARS-CoV-2 which is at least 3.1 log after a contact time of 30 seconds and 3.5 log after two minutes at 20°C under clean conditions. Assays were also performed at 4°C and 37°C, and the results obtained are identical to those obtained at 20°C. This demonstration of the virucidal effect of ionised water against SARS-CoV-2 paves the way for the development of usage as an alternative disinfectant in SARS-CoV-2 control.http://dx.doi.org/10.1155/2022/5995775
spellingShingle Nathalie Wurtz
Issam Hasni
Audrey Bancod
Bernard La Scola
Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
Advances in Virology
title Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
title_full Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
title_fullStr Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
title_full_unstemmed Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
title_short Confirmatory Virucidal Activity of Ionised Active Water S-100® on the SARS-CoV-2 Virus
title_sort confirmatory virucidal activity of ionised active water s 100 r on the sars cov 2 virus
url http://dx.doi.org/10.1155/2022/5995775
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