Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources
Normally, hydroxyapatite (HAp) ceramics have no antimicrobial activity. Therefore, the development of the HAp with enhanced antimicrobial characteristics is essential for the prevention of infections associated with medical implants. In this research article, porous hydroxyapatite (HAp) ceramics wer...
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| Format: | Article |
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Taylor & Francis Group
2025-01-01
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| Series: | Journal of Asian Ceramic Societies |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21870764.2025.2463164 |
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| author | Jatsada Wadthanakul Phanrawee Sriprapha Narongdech Boothrawong Komsanti Chokethawai Chamnan Randorn Waraporn Boontakam Nopakarn Chandet Kriangkrai Thongkorn Gobwute Rujijanagul |
| author_facet | Jatsada Wadthanakul Phanrawee Sriprapha Narongdech Boothrawong Komsanti Chokethawai Chamnan Randorn Waraporn Boontakam Nopakarn Chandet Kriangkrai Thongkorn Gobwute Rujijanagul |
| author_sort | Jatsada Wadthanakul |
| collection | DOAJ |
| description | Normally, hydroxyapatite (HAp) ceramics have no antimicrobial activity. Therefore, the development of the HAp with enhanced antimicrobial characteristics is essential for the prevention of infections associated with medical implants. In this research article, porous hydroxyapatite (HAp) ceramics were synthesized via a simple thermal decomposition of bovine bone. All synthesized samples contained the main phase of HAp. However, beta tricalcium phosphate (β-TCP) started to form at 900°C, and its amount increased with increasing firing temperatures. Crystallite size increased with firing temperatures then dropped at temperatures > 1200°C. The decrease of this value was related to the β-TCP formation. Microstructural analysis revealed that the 900°C sample had a good uniform porous structure with an average pore size of 0.39 μm. The 900°C samples were coated with antimicrobial agents, including Ag-based agents (Ag nanoparticles and AgNO3) and natural plant oils (lemongrass and turmeric oils), to improve their antimicrobial activity. The samples coated with Ag-based agents presented good antimicrobial efficiency while natural plant oil-coated samples showed moderate efficiency. The obtained results suggested the possibility of developing porous samples for antimicrobial applications, using natural sources at a low cost. |
| format | Article |
| id | doaj-art-d78bebcbff6e4bda9d49e3a1e8833e46 |
| institution | OA Journals |
| issn | 2187-0764 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Asian Ceramic Societies |
| spelling | doaj-art-d78bebcbff6e4bda9d49e3a1e8833e462025-08-20T01:56:56ZengTaylor & Francis GroupJournal of Asian Ceramic Societies2187-07642025-01-0113111612510.1080/21870764.2025.2463164Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sourcesJatsada Wadthanakul0Phanrawee Sriprapha1Narongdech Boothrawong2Komsanti Chokethawai3Chamnan Randorn4Waraporn Boontakam5Nopakarn Chandet6Kriangkrai Thongkorn7Gobwute Rujijanagul8Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandDepartment of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandDepartment of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandDepartment of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandMaterials Science Research Center, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandDepartment of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandDepartment of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandThe Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, ThailandDepartment of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, ThailandNormally, hydroxyapatite (HAp) ceramics have no antimicrobial activity. Therefore, the development of the HAp with enhanced antimicrobial characteristics is essential for the prevention of infections associated with medical implants. In this research article, porous hydroxyapatite (HAp) ceramics were synthesized via a simple thermal decomposition of bovine bone. All synthesized samples contained the main phase of HAp. However, beta tricalcium phosphate (β-TCP) started to form at 900°C, and its amount increased with increasing firing temperatures. Crystallite size increased with firing temperatures then dropped at temperatures > 1200°C. The decrease of this value was related to the β-TCP formation. Microstructural analysis revealed that the 900°C sample had a good uniform porous structure with an average pore size of 0.39 μm. The 900°C samples were coated with antimicrobial agents, including Ag-based agents (Ag nanoparticles and AgNO3) and natural plant oils (lemongrass and turmeric oils), to improve their antimicrobial activity. The samples coated with Ag-based agents presented good antimicrobial efficiency while natural plant oil-coated samples showed moderate efficiency. The obtained results suggested the possibility of developing porous samples for antimicrobial applications, using natural sources at a low cost.https://www.tandfonline.com/doi/10.1080/21870764.2025.2463164Biomaterialshydroxyapatiteporous materialsantimicrobial activitynatural source |
| spellingShingle | Jatsada Wadthanakul Phanrawee Sriprapha Narongdech Boothrawong Komsanti Chokethawai Chamnan Randorn Waraporn Boontakam Nopakarn Chandet Kriangkrai Thongkorn Gobwute Rujijanagul Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources Journal of Asian Ceramic Societies Biomaterials hydroxyapatite porous materials antimicrobial activity natural source |
| title | Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources |
| title_full | Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources |
| title_fullStr | Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources |
| title_full_unstemmed | Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources |
| title_short | Investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources |
| title_sort | investigation of the bioactivity and antibacterial activity of porous hydroxyapatite ceramics derived from natural sources |
| topic | Biomaterials hydroxyapatite porous materials antimicrobial activity natural source |
| url | https://www.tandfonline.com/doi/10.1080/21870764.2025.2463164 |
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