Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection
Purpose. To describe liver imaging reporting and data system (LI-RADS) version 2018 and other MRI imaging features in intrahepatic mass-forming cholangiocarcinoma (iCCA) in Chinese adults with vs. without chronic hepatitis B viral (HBV) infection. Methods. We retrospectively enrolled 89 patients wit...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Canadian Journal of Gastroenterology and Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2021/6639600 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832568601840713728 |
|---|---|
| author | Ying-ying Liang Shuo Shao Sichi Kuang Jingbiao Chen Jing Zhou Bingjun He Linqi Zhang Yao Zhang Kathryn J. Fowler Jin Wang |
| author_facet | Ying-ying Liang Shuo Shao Sichi Kuang Jingbiao Chen Jing Zhou Bingjun He Linqi Zhang Yao Zhang Kathryn J. Fowler Jin Wang |
| author_sort | Ying-ying Liang |
| collection | DOAJ |
| description | Purpose. To describe liver imaging reporting and data system (LI-RADS) version 2018 and other MRI imaging features in intrahepatic mass-forming cholangiocarcinoma (iCCA) in Chinese adults with vs. without chronic hepatitis B viral (HBV) infection. Methods. We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. Based on whether patients had chronic HBV, iCCA was divided into two subgroups: HBV-positive (n = 50 patients, including 9 with cirrhosis) vs. HBV-negative (n = 39 patients, including 14 with hepatolithiasis and 25 with no identifiable risk factor for iCCA; none had cirrhosis). Two independent abdominal radiologists in consensus reviewed the largest mass in each patient to assign LI-RADS v2018 features; they also scored each observation’s shape and location. Imaging features were compared using chi-square or Fisher’s exact tests. Results. Most iCCAs in HBV-positive (88% (44/50)) and HBV-negative (97% (38/39)) patients had at least one LR-M feature. Compared to iCCAs in HBV-negative patients, iCCAs in HBV-positive patients were more likely to have at least one major feature of HCC (46% (23/50) vs. 8% (3/39), P < 0.001) and more likely to be smooth (42% (21/50) vs. 10% (4/39), P = 0.001). Six of 50 (12%) iCCAs in HBV-positive patients and 1/39 (3%) iCCAs in HBV-negative patients had at least one major feature of HCC without any LR-M feature. Conclusions. In this retrospective single-center study in Chinese adults, iCCAs in HBV-positive patients were more likely to resemble HCCs than iCCAs in HBV-negative patients. |
| format | Article |
| id | doaj-art-d73f6ebdbf014b28b4a2d3d85db1b9e4 |
| institution | Kabale University |
| issn | 2291-2789 2291-2797 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology and Hepatology |
| spelling | doaj-art-d73f6ebdbf014b28b4a2d3d85db1b9e42025-02-03T00:58:47ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972021-01-01202110.1155/2021/66396006639600Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral InfectionYing-ying Liang0Shuo Shao1Sichi Kuang2Jingbiao Chen3Jing Zhou4Bingjun He5Linqi Zhang6Yao Zhang7Kathryn J. Fowler8Jin Wang9Department of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaShandong Medical Imaging Research Institute, Shandong University, Jinan, Shandong, ChinaDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaDepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaLiver Imaging Group, Department of Radiology, University of California, San Diego, La Jolla, CA, USADepartment of Radiology, The Third Affiliated Hospital of Sun Yat-Sen University, 600 Tianhe Rd., Guangzhou 510630, Guangdong, ChinaPurpose. To describe liver imaging reporting and data system (LI-RADS) version 2018 and other MRI imaging features in intrahepatic mass-forming cholangiocarcinoma (iCCA) in Chinese adults with vs. without chronic hepatitis B viral (HBV) infection. Methods. We retrospectively enrolled 89 patients with pathologically proven iCCA after multiphase imaging performed between 2004 and 2017 at a tertiary medical center in southern China. Based on whether patients had chronic HBV, iCCA was divided into two subgroups: HBV-positive (n = 50 patients, including 9 with cirrhosis) vs. HBV-negative (n = 39 patients, including 14 with hepatolithiasis and 25 with no identifiable risk factor for iCCA; none had cirrhosis). Two independent abdominal radiologists in consensus reviewed the largest mass in each patient to assign LI-RADS v2018 features; they also scored each observation’s shape and location. Imaging features were compared using chi-square or Fisher’s exact tests. Results. Most iCCAs in HBV-positive (88% (44/50)) and HBV-negative (97% (38/39)) patients had at least one LR-M feature. Compared to iCCAs in HBV-negative patients, iCCAs in HBV-positive patients were more likely to have at least one major feature of HCC (46% (23/50) vs. 8% (3/39), P < 0.001) and more likely to be smooth (42% (21/50) vs. 10% (4/39), P = 0.001). Six of 50 (12%) iCCAs in HBV-positive patients and 1/39 (3%) iCCAs in HBV-negative patients had at least one major feature of HCC without any LR-M feature. Conclusions. In this retrospective single-center study in Chinese adults, iCCAs in HBV-positive patients were more likely to resemble HCCs than iCCAs in HBV-negative patients.http://dx.doi.org/10.1155/2021/6639600 |
| spellingShingle | Ying-ying Liang Shuo Shao Sichi Kuang Jingbiao Chen Jing Zhou Bingjun He Linqi Zhang Yao Zhang Kathryn J. Fowler Jin Wang Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection Canadian Journal of Gastroenterology and Hepatology |
| title | Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection |
| title_full | Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection |
| title_fullStr | Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection |
| title_full_unstemmed | Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection |
| title_short | Liver Imaging and Data System (LI-RADS) Version 2018 and Other Imaging Features in Intrahepatic Cholangiocarcinoma in Chinese Adults with vs. without Chronic Hepatitis B Viral Infection |
| title_sort | liver imaging and data system li rads version 2018 and other imaging features in intrahepatic cholangiocarcinoma in chinese adults with vs without chronic hepatitis b viral infection |
| url | http://dx.doi.org/10.1155/2021/6639600 |
| work_keys_str_mv | AT yingyingliang liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT shuoshao liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT sichikuang liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT jingbiaochen liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT jingzhou liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT bingjunhe liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT linqizhang liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT yaozhang liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT kathrynjfowler liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection AT jinwang liverimaginganddatasystemliradsversion2018andotherimagingfeaturesinintrahepaticcholangiocarcinomainchineseadultswithvswithoutchronichepatitisbviralinfection |