Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis
Although end-stage renal disease (ESRD) related to AA amyloidosis nephropathy secondary to tuberculosis is most common in our country, there are limited data concerning patient and graft outcome after renal transplantation (RTx). To the best of our knowledge, this is the first report of RTx in ESRD...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2013/353529 |
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| author | Vivek B. Kute Aruna V. Vanikar Himanshu V. Patel Manoj R. Gumber Pankaj R. Shah Pranjal R. Modi Hargovind L. Trivedi |
| author_facet | Vivek B. Kute Aruna V. Vanikar Himanshu V. Patel Manoj R. Gumber Pankaj R. Shah Pranjal R. Modi Hargovind L. Trivedi |
| author_sort | Vivek B. Kute |
| collection | DOAJ |
| description | Although end-stage renal disease (ESRD) related to AA amyloidosis nephropathy secondary to tuberculosis is most common in our country, there are limited data concerning patient and graft outcome after renal transplantation (RTx). To the best of our knowledge, this is the first report of RTx in ESRD patient with secondary amyloidosis due to tuberculosis from India. A 30-year-old female with past history of pulmonary tuberculosis 3 years back was admitted with complaint of gradually progressive pedal oedema and nausea for 3 months. Renal biopsy was suggestive of secondary renal amyloidosis with vascular involvement and chronic tubulointerstitial involvement. She was transplanted with kidney from her 28-year-old brother with 3/6 human leukocyte antigen match. She had immediate good graft function without any perioperative complications (cardiovascular, infections, rejection and delayed graft function). She was discharged with serum creatinine of 0.8 mg/dL. Her last serum creatinine level was 0.9 mg/dL with cyclosporine level of 100 mg/dL at 9-month followup without any medical or surgical complication. The quality of life also improved after transplantation. With careful selection, ESRD patients with secondary amyloidosis due to tuberculosis are eligible for RTx with favorable outcome and improved quality of life. |
| format | Article |
| id | doaj-art-d73b7b54f84b4dfbbe5e64230ada1015 |
| institution | Kabale University |
| issn | 2090-6943 2090-6951 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-d73b7b54f84b4dfbbe5e64230ada10152025-02-03T01:03:43ZengWileyCase Reports in Transplantation2090-69432090-69512013-01-01201310.1155/2013/353529353529Renal Transplantation in Secondary Amyloidosis Associated with TuberculosisVivek B. Kute0Aruna V. Vanikar1Himanshu V. Patel2Manoj R. Gumber3Pankaj R. Shah4Pranjal R. Modi5Hargovind L. Trivedi6Department of Nephrology and Clinical Transplantation, Institute of Kidney Diseases & Research Center, Dr. H. L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat 380016, IndiaDepartment of Pathology, Laboratory Medicine, Transfusion Services and Immunohematology, IKDRC-ITS, Ahmedabad, IndiaDepartment of Nephrology and Clinical Transplantation, Institute of Kidney Diseases & Research Center, Dr. H. L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat 380016, IndiaDepartment of Nephrology and Clinical Transplantation, Institute of Kidney Diseases & Research Center, Dr. H. L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat 380016, IndiaDepartment of Nephrology and Clinical Transplantation, Institute of Kidney Diseases & Research Center, Dr. H. L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat 380016, IndiaDepartment of Urology and Transplantation, IKDRC-ITS, Ahmedabad, IndiaDepartment of Nephrology and Clinical Transplantation, Institute of Kidney Diseases & Research Center, Dr. H. L. Trivedi Institute of Transplantation Sciences (IKDRC-ITS), Civil Hospital Campus, Asarwa, Ahmedabad, Gujarat 380016, IndiaAlthough end-stage renal disease (ESRD) related to AA amyloidosis nephropathy secondary to tuberculosis is most common in our country, there are limited data concerning patient and graft outcome after renal transplantation (RTx). To the best of our knowledge, this is the first report of RTx in ESRD patient with secondary amyloidosis due to tuberculosis from India. A 30-year-old female with past history of pulmonary tuberculosis 3 years back was admitted with complaint of gradually progressive pedal oedema and nausea for 3 months. Renal biopsy was suggestive of secondary renal amyloidosis with vascular involvement and chronic tubulointerstitial involvement. She was transplanted with kidney from her 28-year-old brother with 3/6 human leukocyte antigen match. She had immediate good graft function without any perioperative complications (cardiovascular, infections, rejection and delayed graft function). She was discharged with serum creatinine of 0.8 mg/dL. Her last serum creatinine level was 0.9 mg/dL with cyclosporine level of 100 mg/dL at 9-month followup without any medical or surgical complication. The quality of life also improved after transplantation. With careful selection, ESRD patients with secondary amyloidosis due to tuberculosis are eligible for RTx with favorable outcome and improved quality of life.http://dx.doi.org/10.1155/2013/353529 |
| spellingShingle | Vivek B. Kute Aruna V. Vanikar Himanshu V. Patel Manoj R. Gumber Pankaj R. Shah Pranjal R. Modi Hargovind L. Trivedi Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis Case Reports in Transplantation |
| title | Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis |
| title_full | Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis |
| title_fullStr | Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis |
| title_full_unstemmed | Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis |
| title_short | Renal Transplantation in Secondary Amyloidosis Associated with Tuberculosis |
| title_sort | renal transplantation in secondary amyloidosis associated with tuberculosis |
| url | http://dx.doi.org/10.1155/2013/353529 |
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