Cadmium disrupted homeostasis of proximal renal tubular cells via targeting ATF4-CHOP complex into the nucleus

Cadmium disrupted homeostasis of proximal renal tubular cells via targeting ATF4-CHOP complex into the nucleus

Cadmium, a ubiquitous toxic metal and environmental pollutant, is associated with several renal metabolic disorders and disrupts the homeostasis of kidneys in humans and animals. However, the precise molecular mechanism remains poorly elucidated. The present study investigated the role of the ATF4-C...

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Bibliographic Details
Main Authors: Muhammad Asmat Ullah Saleem, Ying-Xin Zhao, Farhat Bano, Yi-Xi Tang, Mu-Zi Li, Kanwar Kumar Malhi, Xiao-Wei Li, Xue-Nan Li, Yi Zhao, Jin-Long Li
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Poultry Science
Subjects:
Cadmium
Kidney
Homeostasis
Nephrotoxicity
ATF4-CHOP axis
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125002986
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