Drying of Functional Hydrogels: Development of a Workflow for Bioreactor-Integrated Freeze-Drying of Protein-Coated Alginate Microcarriers for iPS Cell-Based Screenings

Drying of Functional Hydrogels: Development of a Workflow for Bioreactor-Integrated Freeze-Drying of Protein-Coated Alginate Microcarriers for iPS Cell-Based Screenings

Protein-coated ultra-high viscosity (UHV)-alginate hydrogels are essential to mimic the physiological in vivo environment of humans in several in vitro applications. This work presents an optimized bioreactor-integrated freeze-drying process for Matrigel<sup>TM</sup>-coated UHV-alginate...

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Bibliographic Details
Main Authors: Johnn Majd Balsters, Alexander Bäumchen, Michael Roland, Stefan Diebels, Julia C. Neubauer, Michael M. Gepp, Heiko Zimmermann
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Gels
Subjects:
suspension bioreactor
drug discovery
pluripotent stem cells
freeze-drying
(UHV)-alginate
tissue engineering
Online Access:https://www.mdpi.com/2310-2861/11/6/439
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