Design, synthesis and characterization of a new series of 2,3-dihydroquinazolin-4(1H)-one (DHQZ-1) derivatives and evaluation of antitumor resistant (by Molecule Docking)

Design, synthesis and characterization of a new series of 2,3-dihydroquinazolin-4(1H)-one (DHQZ-1) derivatives and evaluation of antitumor resistant (by Molecule Docking)

The objective of this work is to use multicomponent reactions (MCRs) to produce a novel series of quinazoline derivatives with high yield. This occurs in one-pot condensation among Pyridine-3-carbaldehyde with 1H-3,1-benzoxazine-2,4-dione (Isatoic anhydride) and primary amines (3-7). The mixture re...

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Bibliographic Details
Main Authors: Mohammed Abed Kadhim, Emad Khelil Mohammed Zangana, Arkan Hassan Jawad
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2024-07-01
Series:مجلة بغداد للعلوم
Subjects:
Antitumor resistant (protein 1M17), 2,3-Dihydroquinazolin4(1H)-one (DHQZ-1), Isatoic anhydride, Multi-component reactions (MCRs), Molecular Docking, Pyridine-3-carbaldehyde
Online Access:https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8232
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