Immunomodulatory mechanisms of the gut microbiota and metabolites on regulatory T cells in rheumatoid arthritis

Immunomodulatory mechanisms of the gut microbiota and metabolites on regulatory T cells in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease, in which the abnormal activation and proliferation of effector T cells play a pivotal role in its pathogenesis. Regulatory T cells (Tregs) are a unique subset of immune cells with immunosuppressive functions, which help to inhibit the differentiati...

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Bibliographic Details
Main Authors: Xuan Xu, Jingying Zhou, Haihua Xie, Ruhan Zhang, Bowen Gu, Li Liu, Mi Liu, Xiaorong Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
gut microbiota
metabolites
rheumatoid arthritis
regulatory T cells
autoimmune
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1610254/full
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