The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both
Gestational diabetes mellitus (GDM) is defined as the glucose intolerance that is not present or recognized prior to pregnancy. Several risk factors of GDM depend on environmental factors that are thought to regulate the genome through epigenetic mechanisms. Thus, epigenetic regulation could be invo...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2010/605163 |
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| author | J. L. Fernández-Morera S. Rodríguez-Rodero E. Menéndez-Torre M. F. Fraga |
| author_facet | J. L. Fernández-Morera S. Rodríguez-Rodero E. Menéndez-Torre M. F. Fraga |
| author_sort | J. L. Fernández-Morera |
| collection | DOAJ |
| description | Gestational diabetes mellitus (GDM) is defined as the glucose intolerance that is not present or recognized prior to pregnancy. Several risk factors of GDM depend on environmental factors that are thought to regulate the genome through epigenetic mechanisms. Thus, epigenetic regulation could be involved in the development of GDM. In addition, the adverse intrauterine environment in patients with GDM could also have a negative impact on the establishment of the epigenomes of the offspring. |
| format | Article |
| id | doaj-art-d6d4cbea597f451a9734a8bc02757e56 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-d6d4cbea597f451a9734a8bc02757e562025-02-03T05:52:33ZengWileyObstetrics and Gynecology International1687-95891687-95972010-01-01201010.1155/2010/605163605163The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or BothJ. L. Fernández-Morera0S. Rodríguez-Rodero1E. Menéndez-Torre2M. F. Fraga3Endocrinology and Nutrition Service, Hospital Universitario Central de Asturias, Av. Julian Clavería s/n, 33006 Oviedo, SpainCancer Epigenetics Laboratory, Instituto Universitario de Oncología del Principado de Asturias (IUOPA), Universidad de Oviedo, HUCA, 33006 Oviedo, SpainEndocrinology and Nutrition Service, Hospital Universitario Central de Asturias, Av. Julian Clavería s/n, 33006 Oviedo, SpainDepartment of Immunology and Oncology, National Center for Biotechnology, CNB-CSIC, Cantoblanco, 28049 Madrid, SpainGestational diabetes mellitus (GDM) is defined as the glucose intolerance that is not present or recognized prior to pregnancy. Several risk factors of GDM depend on environmental factors that are thought to regulate the genome through epigenetic mechanisms. Thus, epigenetic regulation could be involved in the development of GDM. In addition, the adverse intrauterine environment in patients with GDM could also have a negative impact on the establishment of the epigenomes of the offspring.http://dx.doi.org/10.1155/2010/605163 |
| spellingShingle | J. L. Fernández-Morera S. Rodríguez-Rodero E. Menéndez-Torre M. F. Fraga The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both Obstetrics and Gynecology International |
| title | The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both |
| title_full | The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both |
| title_fullStr | The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both |
| title_full_unstemmed | The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both |
| title_short | The Possible Role of Epigenetics in Gestational Diabetes: Cause, Consequence, or Both |
| title_sort | possible role of epigenetics in gestational diabetes cause consequence or both |
| url | http://dx.doi.org/10.1155/2010/605163 |
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