Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.

<h4>Background</h4>The COVID-19 pandemic is one of the most devastating public health emergencies of international concern to have occurred in the past century. To ensure a safe, scalable, and sustainable response, it is imperative to understand the burden of disease, epidemiological tre...

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Main Authors: Gizaw Teka, Adane Woldeab, Nebiyu Dereje, Frehywot Eshetu, Lehageru Gizachew, Zelalem Tazu, Leuel Lisanwork, Eyasu Tigabu, Ayele Gebeyehu, Adamu Tayachew, Mengistu Biru, Tsegaye Berkessa, Abrham Keraleme, Fentahun Bikale, Wolde Shure, Admikew Agune, Bizuwork Haile, Beza Addis, Muluken Moges, Melaku Gonta, Aster Hailemariam, Laura Binkley, Saira Nawaz, Shu-Hua Wang, Zelalem Mekuria, Ayalew Aklilu, Jemal Aliy, Sileshi Lulseged, Abiy Girmay, Abok Patrick, Berhanu Amare, Hulemenaw Delelegn, Sharon Daves, Getnet Yimer, Ebba Abate, Mesfin Wossen, Zenebe Melaku, Wondwossen Gebreyes, Desmond E Williams, Aschalew Abayneh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLOS Global Public Health
Online Access:https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0003175&type=printable
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author Gizaw Teka
Adane Woldeab
Nebiyu Dereje
Frehywot Eshetu
Lehageru Gizachew
Zelalem Tazu
Leuel Lisanwork
Eyasu Tigabu
Ayele Gebeyehu
Adamu Tayachew
Mengistu Biru
Tsegaye Berkessa
Abrham Keraleme
Fentahun Bikale
Wolde Shure
Admikew Agune
Bizuwork Haile
Beza Addis
Muluken Moges
Melaku Gonta
Aster Hailemariam
Laura Binkley
Saira Nawaz
Shu-Hua Wang
Zelalem Mekuria
Ayalew Aklilu
Jemal Aliy
Sileshi Lulseged
Abiy Girmay
Abok Patrick
Berhanu Amare
Hulemenaw Delelegn
Sharon Daves
Getnet Yimer
Ebba Abate
Mesfin Wossen
Zenebe Melaku
Wondwossen Gebreyes
Desmond E Williams
Aschalew Abayneh
author_facet Gizaw Teka
Adane Woldeab
Nebiyu Dereje
Frehywot Eshetu
Lehageru Gizachew
Zelalem Tazu
Leuel Lisanwork
Eyasu Tigabu
Ayele Gebeyehu
Adamu Tayachew
Mengistu Biru
Tsegaye Berkessa
Abrham Keraleme
Fentahun Bikale
Wolde Shure
Admikew Agune
Bizuwork Haile
Beza Addis
Muluken Moges
Melaku Gonta
Aster Hailemariam
Laura Binkley
Saira Nawaz
Shu-Hua Wang
Zelalem Mekuria
Ayalew Aklilu
Jemal Aliy
Sileshi Lulseged
Abiy Girmay
Abok Patrick
Berhanu Amare
Hulemenaw Delelegn
Sharon Daves
Getnet Yimer
Ebba Abate
Mesfin Wossen
Zenebe Melaku
Wondwossen Gebreyes
Desmond E Williams
Aschalew Abayneh
author_sort Gizaw Teka
collection DOAJ
description <h4>Background</h4>The COVID-19 pandemic is one of the most devastating public health emergencies of international concern to have occurred in the past century. To ensure a safe, scalable, and sustainable response, it is imperative to understand the burden of disease, epidemiological trends, and responses to activities that have already been implemented. We aimed to analyze how COVID-19 tests, cases, and deaths varied by time and region in the general population and healthcare workers (HCWs) in Ethiopia.<h4>Methods</h4>COVID-19 data were captured between October 01, 2021, and September 30, 2022, in 64 systematically selected health facilities throughout Ethiopia. The number of health facilities included in the study was proportionally allocated to the regional states of Ethiopia. Data were captured by standardized tools and formats. Analysis of COVID-19 testing performed, cases detected, and deaths registered by region and time was carried out.<h4>Results</h4>We analyzed 215,024 individuals' data that were captured through COVID-19 surveillance in Ethiopia. Of the 215,024 total tests, 18,964 COVID-19 cases (8.8%, 95% CI: 8.7%- 9.0%) were identified and 534 (2.8%, 95% CI: 2.6%- 3.1%) were deceased. The positivity rate ranged from 1% in the Afar region to 15% in the Sidama region. Eight (1.2%, 95% CI: 0.4%- 2.0%) HCWs died out of 664 infected HCWs, of which 81.5% were from Addis Ababa. Three waves of outbreaks were detected during the analysis period, with the highest positivity rate of 35% during the Omicron period and the highest rate of ICU beds and mechanical ventilators (38%) occupied by COVID-19 patients during the Delta period.<h4>Conclusions</h4>The temporal and regional variations in COVID-19 cases and deaths in Ethiopia underscore the need for concerted efforts to address the disparities in the COVID-19 surveillance and response system. These lessons should be critically considered during the integration of the COVID-19 surveillance system into the routine surveillance system.
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institution Kabale University
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publishDate 2024-01-01
publisher Public Library of Science (PLoS)
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spelling doaj-art-d6d44b4cf67d4ac1b00c25cb1594e4682025-08-20T03:25:38ZengPublic Library of Science (PLoS)PLOS Global Public Health2767-33752024-01-0145e000317510.1371/journal.pgph.0003175Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.Gizaw TekaAdane WoldeabNebiyu DerejeFrehywot EshetuLehageru GizachewZelalem TazuLeuel LisanworkEyasu TigabuAyele GebeyehuAdamu TayachewMengistu BiruTsegaye BerkessaAbrham KeralemeFentahun BikaleWolde ShureAdmikew AguneBizuwork HaileBeza AddisMuluken MogesMelaku GontaAster HailemariamLaura BinkleySaira NawazShu-Hua WangZelalem MekuriaAyalew AkliluJemal AliySileshi LulsegedAbiy GirmayAbok PatrickBerhanu AmareHulemenaw DelelegnSharon DavesGetnet YimerEbba AbateMesfin WossenZenebe MelakuWondwossen GebreyesDesmond E WilliamsAschalew Abayneh<h4>Background</h4>The COVID-19 pandemic is one of the most devastating public health emergencies of international concern to have occurred in the past century. To ensure a safe, scalable, and sustainable response, it is imperative to understand the burden of disease, epidemiological trends, and responses to activities that have already been implemented. We aimed to analyze how COVID-19 tests, cases, and deaths varied by time and region in the general population and healthcare workers (HCWs) in Ethiopia.<h4>Methods</h4>COVID-19 data were captured between October 01, 2021, and September 30, 2022, in 64 systematically selected health facilities throughout Ethiopia. The number of health facilities included in the study was proportionally allocated to the regional states of Ethiopia. Data were captured by standardized tools and formats. Analysis of COVID-19 testing performed, cases detected, and deaths registered by region and time was carried out.<h4>Results</h4>We analyzed 215,024 individuals' data that were captured through COVID-19 surveillance in Ethiopia. Of the 215,024 total tests, 18,964 COVID-19 cases (8.8%, 95% CI: 8.7%- 9.0%) were identified and 534 (2.8%, 95% CI: 2.6%- 3.1%) were deceased. The positivity rate ranged from 1% in the Afar region to 15% in the Sidama region. Eight (1.2%, 95% CI: 0.4%- 2.0%) HCWs died out of 664 infected HCWs, of which 81.5% were from Addis Ababa. Three waves of outbreaks were detected during the analysis period, with the highest positivity rate of 35% during the Omicron period and the highest rate of ICU beds and mechanical ventilators (38%) occupied by COVID-19 patients during the Delta period.<h4>Conclusions</h4>The temporal and regional variations in COVID-19 cases and deaths in Ethiopia underscore the need for concerted efforts to address the disparities in the COVID-19 surveillance and response system. These lessons should be critically considered during the integration of the COVID-19 surveillance system into the routine surveillance system.https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0003175&type=printable
spellingShingle Gizaw Teka
Adane Woldeab
Nebiyu Dereje
Frehywot Eshetu
Lehageru Gizachew
Zelalem Tazu
Leuel Lisanwork
Eyasu Tigabu
Ayele Gebeyehu
Adamu Tayachew
Mengistu Biru
Tsegaye Berkessa
Abrham Keraleme
Fentahun Bikale
Wolde Shure
Admikew Agune
Bizuwork Haile
Beza Addis
Muluken Moges
Melaku Gonta
Aster Hailemariam
Laura Binkley
Saira Nawaz
Shu-Hua Wang
Zelalem Mekuria
Ayalew Aklilu
Jemal Aliy
Sileshi Lulseged
Abiy Girmay
Abok Patrick
Berhanu Amare
Hulemenaw Delelegn
Sharon Daves
Getnet Yimer
Ebba Abate
Mesfin Wossen
Zenebe Melaku
Wondwossen Gebreyes
Desmond E Williams
Aschalew Abayneh
Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
PLOS Global Public Health
title Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
title_full Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
title_fullStr Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
title_full_unstemmed Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
title_short Regional and temporal variations in COVID-19 cases and deaths in Ethiopia: Lessons learned from the COVID-19 enhanced surveillance and response.
title_sort regional and temporal variations in covid 19 cases and deaths in ethiopia lessons learned from the covid 19 enhanced surveillance and response
url https://journals.plos.org/globalpublichealth/article/file?id=10.1371/journal.pgph.0003175&type=printable
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