Identification of a new lesch-nyhan syndrome mutation (HPRT BRASIL) and analysis of potentially heterozygous females

The mutation in the hypoxanthine-guanine phosphoribosyltransferase (HPRT) gene has been determined in two brothers affected with Lesch-Nyhan syndrome. Female members of the family who are at risk for being heterozygous carriers of the HPRT mutation were also studied to determine whether they carry t...

Full description

Saved in:
Bibliographic Details
Main Authors: PATRICK O'NEILL, LUCY TROMBLEY, MARY GUNDEL, TIMOTHY HUNTER, JANICE A. NICKLAS, MARA LUCIA S. FERREIRA, MARIA JULIA BUGALLO, ANTÔNIO CARLOS FARIAS, ALFREDO LOHR, MERI DIAMANTOPOULOS, SALMO RASKIN
Format: Article
Language:English
Published: Thieme Revinter Publicações 1999-12-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X1999000600001&tlng=en
Tags: Add Tag
No Tags, Be the first to tag this record!