Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis
Abstract Background Ameloblastoma is the most prevalent odontogenic tumor of the jaw, with a significant recurrence rate. It was conventionally classified radiographically as unilocular or multilocular. As 3D images become more common, there is a need to reassess this classification. This study aime...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12903-025-05485-6 |
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| author | Jo-Eun Kim Jun-Bum Cho Won-Jin Yi Min-Suk Heo Sam-Sun Lee Kyung-Hoe Huh |
| author_facet | Jo-Eun Kim Jun-Bum Cho Won-Jin Yi Min-Suk Heo Sam-Sun Lee Kyung-Hoe Huh |
| author_sort | Jo-Eun Kim |
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| description | Abstract Background Ameloblastoma is the most prevalent odontogenic tumor of the jaw, with a significant recurrence rate. It was conventionally classified radiographically as unilocular or multilocular. As 3D images become more common, there is a need to reassess this classification. This study aimed to conduct a multi-planar assessment of ameloblastoma using CT images, reclassify the lesions based on locularity, and correlate the locularity with imaging characteristics and recurrence. Methods Panoramic radiographs and CT images of histopathologically confirmed 255 ameloblastoma patients were included. The analysis encompassed imaging features including locularity, expansion, thinning, cortical perforation, and root resorption. Image characteristics associated with recurrence rate were examined, and image features were assessed based on locularity. Results On panoramic radiographs, most ameloblastomas (68.6%) were classified as multilocular, while 31.4% were unilocular. The CT scan demonstrated that 46.3% of the ameloblastomas were pseudo-multilocular, 29.4% were unilocular, and 24.3% were multilocular. Multilocular cases on panoramic radiographs often appeared as pseudo-multilocular on CT. Cortical perforation, root resorption, and size were significantly correlated with CT locularity types (p < 0.05). The recurrence rate was 14.11%, and the risk of recurrence was substantially reduced by mandibulectomy and a larger tumor size. No other variables were significantly related to recurrence. Conclusion An accurate diagnosis of ameloblastoma and surgical planning to reduce the recurrence rate are contingent upon the use of three-dimensional imaging modalities, such as CT. |
| format | Article |
| id | doaj-art-d6c135c2b7c948d990afc6d483d84feb |
| institution | Kabale University |
| issn | 1472-6831 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj-art-d6c135c2b7c948d990afc6d483d84feb2025-01-26T12:54:59ZengBMCBMC Oral Health1472-68312025-01-012511910.1186/s12903-025-05485-6Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysisJo-Eun Kim0Jun-Bum Cho1Won-Jin Yi2Min-Suk Heo3Sam-Sun Lee4Kyung-Hoe Huh5Department of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National UniversityDepartment of Oral and Maxillofacial Radiology, School of Dentistry, Seoul National UniversityDepartment of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National UniversityDepartment of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National UniversityDepartment of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National UniversityDepartment of Oral and Maxillofacial Radiology and Dental Research Institute, School of Dentistry, Seoul National UniversityAbstract Background Ameloblastoma is the most prevalent odontogenic tumor of the jaw, with a significant recurrence rate. It was conventionally classified radiographically as unilocular or multilocular. As 3D images become more common, there is a need to reassess this classification. This study aimed to conduct a multi-planar assessment of ameloblastoma using CT images, reclassify the lesions based on locularity, and correlate the locularity with imaging characteristics and recurrence. Methods Panoramic radiographs and CT images of histopathologically confirmed 255 ameloblastoma patients were included. The analysis encompassed imaging features including locularity, expansion, thinning, cortical perforation, and root resorption. Image characteristics associated with recurrence rate were examined, and image features were assessed based on locularity. Results On panoramic radiographs, most ameloblastomas (68.6%) were classified as multilocular, while 31.4% were unilocular. The CT scan demonstrated that 46.3% of the ameloblastomas were pseudo-multilocular, 29.4% were unilocular, and 24.3% were multilocular. Multilocular cases on panoramic radiographs often appeared as pseudo-multilocular on CT. Cortical perforation, root resorption, and size were significantly correlated with CT locularity types (p < 0.05). The recurrence rate was 14.11%, and the risk of recurrence was substantially reduced by mandibulectomy and a larger tumor size. No other variables were significantly related to recurrence. Conclusion An accurate diagnosis of ameloblastoma and surgical planning to reduce the recurrence rate are contingent upon the use of three-dimensional imaging modalities, such as CT.https://doi.org/10.1186/s12903-025-05485-6AmeloblastomaImaging classificationLocularityComputed tomographyPrognosis |
| spellingShingle | Jo-Eun Kim Jun-Bum Cho Won-Jin Yi Min-Suk Heo Sam-Sun Lee Kyung-Hoe Huh Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis BMC Oral Health Ameloblastoma Imaging classification Locularity Computed tomography Prognosis |
| title | Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis |
| title_full | Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis |
| title_fullStr | Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis |
| title_full_unstemmed | Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis |
| title_short | Classification and prognostic evaluation of ameloblastoma using multiplanar CT imaging: a retrospective analysis |
| title_sort | classification and prognostic evaluation of ameloblastoma using multiplanar ct imaging a retrospective analysis |
| topic | Ameloblastoma Imaging classification Locularity Computed tomography Prognosis |
| url | https://doi.org/10.1186/s12903-025-05485-6 |
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