Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama
Objective. To conduct a point prevalence survey (PPS) of antibiotic use in the main pediatric tertiary-level hospital in Panama City to establish antibiotic prevalence and identify key areas for addressing antimicrobial resistance. Methods. This point prevalence survey (PPS) conducted in a tertiary-...
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Pan American Health Organization
2025-01-01
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| Series: | Revista Panamericana de Salud Pública |
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| Online Access: | https://iris.paho.org/handle/10665.2/64100 |
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| author | Ximena Norero Dora Estripeaut Elizabeth Castaño Jacqueline Levy Paola Lichtenberger José Pablo Díaz-Madriz José Luis Bustos Robin Rojas Cortés Gabriel Levy-Hara |
| author_facet | Ximena Norero Dora Estripeaut Elizabeth Castaño Jacqueline Levy Paola Lichtenberger José Pablo Díaz-Madriz José Luis Bustos Robin Rojas Cortés Gabriel Levy-Hara |
| author_sort | Ximena Norero |
| collection | DOAJ |
| description | Objective. To conduct a point prevalence survey (PPS) of antibiotic use in the main pediatric tertiary-level hospital in Panama City to establish antibiotic prevalence and identify key areas for addressing antimicrobial resistance.
Methods. This point prevalence survey (PPS) conducted in a tertiary-level hospital in Panama followed the Pan American Health Organization’s adaptation of the methodology proposed by the World Health Organization for PPSs on antibiotic use. Information obtained included patients’ demographic characteristics, antimicrobial prescriptions, indication for antimicrobial use, and prescription’s adherence to guidelines.
Results. Of 298 patients surveyed from August to September 2023, 176 (59.0%) were treated with antibiotics. The pediatric ward (86.3%) and the neonatal intensive unit (80.0%) had the highest prevalence of antibiotic use. Hospital-acquired infections accounted for 32.6% of antibiotic prescriptions, with piperacillin/tazobactam (29.4%), meropenem (15.3%), amikacin (15.3%), and ampicillin/sulbactam (10.2%) being the most prescribed. Treatment for community-acquired infections represented 55.9% of antibiotic prescriptions, with ampicillin (24.6%), gentamicin (22.6%), and ampicillin/sulbactam (14.0%) being the most frequently used. Of the prescriptions considered in the analysis, 61.0% adhered to hospital guidelines.
Conclusions. This PPS observed a high prevalence of antibiotic use. The findings suggest it is necessary to assess the need for ampicillin, gentamicin, and piperacillin-tazobactam use in patients admitted to pediatric critical care units, with special emphasis on children with pneumonia and sepsis diagnosis, the most common pathologies for which an antimicrobial was prescribed. |
| format | Article |
| id | doaj-art-d6c05abdca03423383541509a4b27e7a |
| institution | Kabale University |
| issn | 1020-4989 1680-5348 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Pan American Health Organization |
| record_format | Article |
| series | Revista Panamericana de Salud Pública |
| spelling | doaj-art-d6c05abdca03423383541509a4b27e7a2025-01-20T08:25:19ZengPan American Health OrganizationRevista Panamericana de Salud Pública1020-49891680-53482025-01-014971810.26633/RPSP.2025.7rpspPoint prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of PanamaXimena Norero0Dora Estripeaut1Elizabeth Castaño2Jacqueline Levy3Paola Lichtenberger4José Pablo Díaz-Madriz5José Luis Bustos6Robin Rojas Cortés7Gabriel Levy-Hara8Hospital del Niño Dr. José Renán Esquivel, Panama City, Republic of Panama.Hospital del Niño Dr. José Renán Esquivel, Panama City, Republic of Panama.Hospital del Niño Dr. José Renán Esquivel, Panama City, Republic of Panama.Hospital del Niño Dr. José Renán Esquivel, Panama City, Republic of Panama.University of Miami Miller School of Medicine, Miami, United States of America.Clínica Bíblica Hospital, San José, Costa Rica.Pan American Health Organization/World Health Organization, Washington, DC, United States of America.Pan American Health Organization/World Health Organization, Washington, DC, United States of America.Infectious Diseases Unit, Hospital Carlos G. Durand, Buenos Aires, Argentina.Objective. To conduct a point prevalence survey (PPS) of antibiotic use in the main pediatric tertiary-level hospital in Panama City to establish antibiotic prevalence and identify key areas for addressing antimicrobial resistance. Methods. This point prevalence survey (PPS) conducted in a tertiary-level hospital in Panama followed the Pan American Health Organization’s adaptation of the methodology proposed by the World Health Organization for PPSs on antibiotic use. Information obtained included patients’ demographic characteristics, antimicrobial prescriptions, indication for antimicrobial use, and prescription’s adherence to guidelines. Results. Of 298 patients surveyed from August to September 2023, 176 (59.0%) were treated with antibiotics. The pediatric ward (86.3%) and the neonatal intensive unit (80.0%) had the highest prevalence of antibiotic use. Hospital-acquired infections accounted for 32.6% of antibiotic prescriptions, with piperacillin/tazobactam (29.4%), meropenem (15.3%), amikacin (15.3%), and ampicillin/sulbactam (10.2%) being the most prescribed. Treatment for community-acquired infections represented 55.9% of antibiotic prescriptions, with ampicillin (24.6%), gentamicin (22.6%), and ampicillin/sulbactam (14.0%) being the most frequently used. Of the prescriptions considered in the analysis, 61.0% adhered to hospital guidelines. Conclusions. This PPS observed a high prevalence of antibiotic use. The findings suggest it is necessary to assess the need for ampicillin, gentamicin, and piperacillin-tazobactam use in patients admitted to pediatric critical care units, with special emphasis on children with pneumonia and sepsis diagnosis, the most common pathologies for which an antimicrobial was prescribed.https://iris.paho.org/handle/10665.2/64100drug resistance, microbialantimicrobial stewardshipprevalencepediatricspanama |
| spellingShingle | Ximena Norero Dora Estripeaut Elizabeth Castaño Jacqueline Levy Paola Lichtenberger José Pablo Díaz-Madriz José Luis Bustos Robin Rojas Cortés Gabriel Levy-Hara Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama Revista Panamericana de Salud Pública drug resistance, microbial antimicrobial stewardship prevalence pediatrics panama |
| title | Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama |
| title_full | Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama |
| title_fullStr | Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama |
| title_full_unstemmed | Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama |
| title_short | Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama |
| title_sort | point prevalence survey of antibiotics in a pediatric tertiary hospital in the republic of panama |
| topic | drug resistance, microbial antimicrobial stewardship prevalence pediatrics panama |
| url | https://iris.paho.org/handle/10665.2/64100 |
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