Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma

Hedgehog Pathway Inhibition Hampers Sphere and Holoclone Formation in Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children and can be divided into two main subtypes: embryonal (eRMS) and alveolar (aRMS). Among the cellular heterogeneity of tumors, the existence of a small fraction of cells called cancer stem cells (CSC), thought to be resp...

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Main Authors: Ana Almazán-Moga, Patricia Zarzosa, Isaac Vidal, Carla Molist, Irina Giralt, Natalia Navarro, Aroa Soriano, Miguel F. Segura, Arantza Alfranca, Javier Garcia-Castro, José Sánchez de Toledo, Josep Roma, Soledad Gallego
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/7507380
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