Perpetuation of inflammation associated with experimental arthritis: the role of macrophage activation by neutrophilic myeloperoxidase

Perpetuation of inflammation associated with experimental arthritis: the role of macrophage activation by neutrophilic myeloperoxidase

Rheumatoid arthritis (RA) is characterized by an abnormal cellular and cytokine infiltration of inflamed joints. This study addresses a previously unrecognized interaction between neutrophilic-myeloperoxidase (MPO) and macrophages (MΦ) which could explain the perpetuation of inflammation associated...

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Bibliographic Details
Main Authors: Monique P. Gelderman, Rodney Stuart, David Vigerust, Steven Fuhrmann, Doris L. Lefkowitz, Robert C. Allen, Stanley S. Lefkowitz, Susan Graham
Format: Article
Language:English
Published: Wiley 1998-01-01
Series:Mediators of Inflammation
Subjects:
Autoimmunity
Peroxidases
TNFα
Rheumatoid arthritis
Reactive oxygen intermediates.
Online Access:http://dx.doi.org/10.1080/09629359890758
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