ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water

Glyphosate is a widely used broad-spectrum herbicide for controlling grassy weeds, despite having potential health hazards. Herein, we report on a solid-state electrochemical sensor based on ZnO nanoparticles (ZnO NPs) for on-site detection of glyphosate. Accordingly, ZnO NPs was drop-cast on the su...

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Main Authors: Zorica Novakovic, Zorka Z. Vasiljevic, Maria Vesna Nikolic, Nenad B. Tadic, Tijana Djordjevic, Marko Radovic, Ivana Gadjanski, Snežana Papović, Filip Vlahovic, Dalibor Stankovic, Jasmina Vidic
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Talanta Open
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Online Access:http://www.sciencedirect.com/science/article/pii/S2666831925000839
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author Zorica Novakovic
Zorka Z. Vasiljevic
Maria Vesna Nikolic
Nenad B. Tadic
Tijana Djordjevic
Marko Radovic
Ivana Gadjanski
Snežana Papović
Filip Vlahovic
Dalibor Stankovic
Jasmina Vidic
author_facet Zorica Novakovic
Zorka Z. Vasiljevic
Maria Vesna Nikolic
Nenad B. Tadic
Tijana Djordjevic
Marko Radovic
Ivana Gadjanski
Snežana Papović
Filip Vlahovic
Dalibor Stankovic
Jasmina Vidic
author_sort Zorica Novakovic
collection DOAJ
description Glyphosate is a widely used broad-spectrum herbicide for controlling grassy weeds, despite having potential health hazards. Herein, we report on a solid-state electrochemical sensor based on ZnO nanoparticles (ZnO NPs) for on-site detection of glyphosate. Accordingly, ZnO NPs was drop-cast on the surface of a disposable screen-printed carbon electrode. Eco-friendly ZnO NPs of only 7 nm crystallite sizes were obtained by green sol-gel synthesis using lemon (Citrus limon) waste aqueous extract as the green reducing and capping/stabilizing agent and Zn nitrate precursor as evidenced by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction and diffuse reflectance. SEM confirmed successful electrode functionalization with the synthesized nanoparticles. Under laboratory conditions in acetate buffer (pH 5), the sensor demonstrated excellent selectivity and sensitivity, with a detection limit of 0.648 µM, a wide linear detection range (0.5 µM to 7.5 mM), and a rapid detection time of 30 min. When tested in river water, the sensor achieved a detection limit of 0.96 µM using differential pulse voltammetry. It also exceptionally tolerated interference from similar organophosphorus compounds and ions commonly found in river water. The excellent detection performance of the sensor was attributed to the strong coordination interactions between Zn atoms and phosphonate/carboxylate groups that are enhanced by a hydrogen bond at acidic pH, as determined by chemical calculations. This disposable sensor offers a cost-effective, efficient, and environmentally friendly solution for monitoring glyphosate in water systems.
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spelling doaj-art-d68cf358f8fd4bef90ca7dc6ea79e4fa2025-08-20T01:59:14ZengElsevierTalanta Open2666-83192025-12-011210048110.1016/j.talo.2025.100481ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in waterZorica Novakovic0Zorka Z. Vasiljevic1Maria Vesna Nikolic2Nenad B. Tadic3Tijana Djordjevic4Marko Radovic5Ivana Gadjanski6Snežana Papović7Filip Vlahovic8Dalibor Stankovic9Jasmina Vidic10University of Novi Sad, BioSense Institute, Dr Zorana Djindjica 1a, 21000 Novi Sad, SerbiaUniversity of Belgrade - Institute for Multidisciplinary Research, Kneza Viseslava 1, 11030 Belgrade, SerbiaUniversity of Belgrade - Institute for Multidisciplinary Research, Kneza Viseslava 1, 11030 Belgrade, SerbiaUniversity of Belgrade, Faculty of Physics, Cara Dusana 13, 11000 Belgrade, SerbiaInstitute of Pesticides and Environmental Protection, Banatska 31b, 11080 Belgrade, SerbiaUniversity of Novi Sad, BioSense Institute, Dr Zorana Djindjica 1a, 21000 Novi Sad, SerbiaUniversity of Novi Sad, BioSense Institute, Dr Zorana Djindjica 1a, 21000 Novi Sad, SerbiaUniversity of Novi Sad, Faculty of Science, Trg Dositeja Obradovica 3, 21000 Novi Sad, SerbiaInstitute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, Njegoseva 12, 11000 Belgrade, SerbiaFaculty of Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, SerbiaUniversité Paris-Saclay, INRAE, AgroParisTech, Micalis Institute, UMR 1319, 78350 Jouy-en-Josas, France; Corresponding author.Glyphosate is a widely used broad-spectrum herbicide for controlling grassy weeds, despite having potential health hazards. Herein, we report on a solid-state electrochemical sensor based on ZnO nanoparticles (ZnO NPs) for on-site detection of glyphosate. Accordingly, ZnO NPs was drop-cast on the surface of a disposable screen-printed carbon electrode. Eco-friendly ZnO NPs of only 7 nm crystallite sizes were obtained by green sol-gel synthesis using lemon (Citrus limon) waste aqueous extract as the green reducing and capping/stabilizing agent and Zn nitrate precursor as evidenced by scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction and diffuse reflectance. SEM confirmed successful electrode functionalization with the synthesized nanoparticles. Under laboratory conditions in acetate buffer (pH 5), the sensor demonstrated excellent selectivity and sensitivity, with a detection limit of 0.648 µM, a wide linear detection range (0.5 µM to 7.5 mM), and a rapid detection time of 30 min. When tested in river water, the sensor achieved a detection limit of 0.96 µM using differential pulse voltammetry. It also exceptionally tolerated interference from similar organophosphorus compounds and ions commonly found in river water. The excellent detection performance of the sensor was attributed to the strong coordination interactions between Zn atoms and phosphonate/carboxylate groups that are enhanced by a hydrogen bond at acidic pH, as determined by chemical calculations. This disposable sensor offers a cost-effective, efficient, and environmentally friendly solution for monitoring glyphosate in water systems.http://www.sciencedirect.com/science/article/pii/S2666831925000839PesticidesEco-friendly ZnO nanoparticlesSensorEnvironmental waterComputational modeling
spellingShingle Zorica Novakovic
Zorka Z. Vasiljevic
Maria Vesna Nikolic
Nenad B. Tadic
Tijana Djordjevic
Marko Radovic
Ivana Gadjanski
Snežana Papović
Filip Vlahovic
Dalibor Stankovic
Jasmina Vidic
ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water
Talanta Open
Pesticides
Eco-friendly ZnO nanoparticles
Sensor
Environmental water
Computational modeling
title ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water
title_full ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water
title_fullStr ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water
title_full_unstemmed ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water
title_short ZnO-nanostructured electrochemical sensor for efficient detection of glyphosate in water
title_sort zno nanostructured electrochemical sensor for efficient detection of glyphosate in water
topic Pesticides
Eco-friendly ZnO nanoparticles
Sensor
Environmental water
Computational modeling
url http://www.sciencedirect.com/science/article/pii/S2666831925000839
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