Investigation of Genipin Cross-Linked Microcapsule for Oral Delivery of Live Bacterial Cells and Other Biotherapeutics: Preparation and In Vitro Analysis in Simulated Human Gastrointestinal Model

Investigation of Genipin Cross-Linked Microcapsule for Oral Delivery of Live Bacterial Cells and Other Biotherapeutics: Preparation and In Vitro Analysis in Simulated Human Gastrointestinal Model

Oral therapy utilizing engineered microorganisms has shown promise in the treatment of many diseases. By microencapsulation, viable cells can overcome the harsh gastrointestinal (GI) environment and secrete needed therapeutics into the gut. These engineered cells should be encased without escaping i...

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Bibliographic Details
Main Authors: Hongmei Chen, Wei Ouyang, Christopher Martoni, Fatemeh Afkhami, Bisi Lawuyi, Trisna Lim, Satya Prakash
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2010/985137
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