Resection or radiofrequency ablation of colorectal liver metastasis
Background/Aim. Liver resection is the treatment of choice for solitary colorectal liver metastases in suitable candidates. Recently, radiofrequency ablation (RFA) has become a very popular procedure in the treatment of liver metastases. The aim of this study was to compare outcomes in pati...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2014-01-01
|
| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501406542J.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850229957537562624 |
|---|---|
| author | Jašarović Damir Stojanović Dragoš Mitrović Nebojša Stevanović Dejan |
| author_facet | Jašarović Damir Stojanović Dragoš Mitrović Nebojša Stevanović Dejan |
| author_sort | Jašarović Damir |
| collection | DOAJ |
| description | Background/Aim. Liver resection is the treatment of choice for solitary
colorectal liver metastases in suitable candidates. Recently, radiofrequency
ablation (RFA) has become a very popular procedure in the treatment of liver
metastases. The aim of this study was to compare outcomes in patients with
solitary colorectal liver metastasis who had been subjected to resection or
ablation. Methods. In this retrospective study we analyzed and compared
patients with solitary colorectal liver metastases treated by resection or
ablation in the University Hospital Centre “Dr Dragiša Mišović” in Belgrade
from January 2002 until December 2009. Results. In this study 94 (67.1%)
patients underwent resection whereas 46 (32.9%) patients underwent RFA. Most
of the resected patients (59.6%) required major hepatectomy. The median
follow-up time was 28.4 months. Tumor ablation was a significant predictor of
the overall survival (p = 0.002; OR 3.75; 95% CI 1.696-8.284). Our study
demonstrated longer disease free-survival in the group of resected patients
compared to the RFA group (37.6 vs 22.3 months, p = 0.073). The median
overall survival was 56.3 months for patients who underwent resection vs 25.1
months for those in the RFA group (p = 0.005). Conclusion. This study shows
that the patients with solitary hepatic colorectal cancer metastases should
be considered for hepatic resection whenever it is feasible, because this
procedure provides superior long-term survival as compared to radiofrequency
ablation. |
| format | Article |
| id | doaj-art-d67ce1199e7941d7b35689a6b6657c3b |
| institution | OA Journals |
| issn | 0042-8450 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-d67ce1199e7941d7b35689a6b6657c3b2025-08-20T02:04:01ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502014-01-0171654254610.2298/VSP1406542J0042-84501406542JResection or radiofrequency ablation of colorectal liver metastasisJašarović Damir0Stojanović Dragoš1Mitrović Nebojša2Stevanović Dejan3Clinical Hospital Center Zemun, BelgradeClinical Hospital Center Zemun, BelgradeClinical Hospital Center Zemun, BelgradeClinical Hospital Center Zemun, BelgradeBackground/Aim. Liver resection is the treatment of choice for solitary colorectal liver metastases in suitable candidates. Recently, radiofrequency ablation (RFA) has become a very popular procedure in the treatment of liver metastases. The aim of this study was to compare outcomes in patients with solitary colorectal liver metastasis who had been subjected to resection or ablation. Methods. In this retrospective study we analyzed and compared patients with solitary colorectal liver metastases treated by resection or ablation in the University Hospital Centre “Dr Dragiša Mišović” in Belgrade from January 2002 until December 2009. Results. In this study 94 (67.1%) patients underwent resection whereas 46 (32.9%) patients underwent RFA. Most of the resected patients (59.6%) required major hepatectomy. The median follow-up time was 28.4 months. Tumor ablation was a significant predictor of the overall survival (p = 0.002; OR 3.75; 95% CI 1.696-8.284). Our study demonstrated longer disease free-survival in the group of resected patients compared to the RFA group (37.6 vs 22.3 months, p = 0.073). The median overall survival was 56.3 months for patients who underwent resection vs 25.1 months for those in the RFA group (p = 0.005). Conclusion. This study shows that the patients with solitary hepatic colorectal cancer metastases should be considered for hepatic resection whenever it is feasible, because this procedure provides superior long-term survival as compared to radiofrequency ablation.http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501406542J.pdfcolorectal neoplasmsdigestive system surgical proceduresliver neoplasmsneoplasm metastasiscatheter ablation, treatment outcome |
| spellingShingle | Jašarović Damir Stojanović Dragoš Mitrović Nebojša Stevanović Dejan Resection or radiofrequency ablation of colorectal liver metastasis Vojnosanitetski Pregled colorectal neoplasms digestive system surgical procedures liver neoplasms neoplasm metastasis catheter ablation, treatment outcome |
| title | Resection or radiofrequency ablation of colorectal liver metastasis |
| title_full | Resection or radiofrequency ablation of colorectal liver metastasis |
| title_fullStr | Resection or radiofrequency ablation of colorectal liver metastasis |
| title_full_unstemmed | Resection or radiofrequency ablation of colorectal liver metastasis |
| title_short | Resection or radiofrequency ablation of colorectal liver metastasis |
| title_sort | resection or radiofrequency ablation of colorectal liver metastasis |
| topic | colorectal neoplasms digestive system surgical procedures liver neoplasms neoplasm metastasis catheter ablation, treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501406542J.pdf |
| work_keys_str_mv | AT jasarovicdamir resectionorradiofrequencyablationofcolorectallivermetastasis AT stojanovicdragos resectionorradiofrequencyablationofcolorectallivermetastasis AT mitrovicnebojsa resectionorradiofrequencyablationofcolorectallivermetastasis AT stevanovicdejan resectionorradiofrequencyablationofcolorectallivermetastasis |