Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde
In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by taking DMF as solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized by IR, 1HNMR and mass spectral analys...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2011/265329 |
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| author | Priyanka Kamaria N. Kawathekar Prerna Chaturvedi |
| author_facet | Priyanka Kamaria N. Kawathekar Prerna Chaturvedi |
| author_sort | Priyanka Kamaria |
| collection | DOAJ |
| description | In order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by taking DMF as solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized by IR, 1HNMR and mass spectral analysis. All compounds were tested against five gram positive and five gram negative bacterial strains and one fungal strain. All compounds exhibited better activity against gram positive strains than against gram negative strains and the compounds were found more active against S.aureus and B.subtilis. |
| format | Article |
| id | doaj-art-d666183470d04f559d24c2a76bf9fec0 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-d666183470d04f559d24c2a76bf9fec02025-02-03T01:33:06ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-018130531110.1155/2011/265329Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehydePriyanka Kamaria0N. Kawathekar1Prerna Chaturvedi2Department of Pharmacy Shri Govindram Seksaria Institute of Technology and Science, 23-Park Road, Indore-452003, IndiaDepartment of Pharmacy Shri Govindram Seksaria Institute of Technology and Science, 23-Park Road, Indore-452003, IndiaDepartment of Pharmacy Shri Govindram Seksaria Institute of Technology and Science, 23-Park Road, Indore-452003, IndiaIn order to develop new antimicrobial agents, a series of Schiff bases of indole-3-aldehyde were synthesized by microwave assisted synthesis by taking DMF as solvent and evaluated for their antimicrobial activity. All the synthesized compounds were characterized by IR, 1HNMR and mass spectral analysis. All compounds were tested against five gram positive and five gram negative bacterial strains and one fungal strain. All compounds exhibited better activity against gram positive strains than against gram negative strains and the compounds were found more active against S.aureus and B.subtilis.http://dx.doi.org/10.1155/2011/265329 |
| spellingShingle | Priyanka Kamaria N. Kawathekar Prerna Chaturvedi Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde E-Journal of Chemistry |
| title | Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde |
| title_full | Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde |
| title_fullStr | Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde |
| title_full_unstemmed | Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde |
| title_short | Microwave Assisted Synthesis and Antimicrobial Evaluation of Schiff Bases of Indole-3-aldehyde |
| title_sort | microwave assisted synthesis and antimicrobial evaluation of schiff bases of indole 3 aldehyde |
| url | http://dx.doi.org/10.1155/2011/265329 |
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