COVID-19 and Mucormycosis Coinfection: How Challenging It Is
Recently, cases of rhinoorbital mucormycosis in people diagnosed with COVID-19 have been reported from India particularly. Diabetes mellitus though happens to be an independent risk factor both for severe COVID-19 and mucormycosis, administration of steroids is attributed as a precipitating factor f...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/2022/8617212 |
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| author | Niranjan Nayak Erum Khan Debadatta Panigrahi |
| author_facet | Niranjan Nayak Erum Khan Debadatta Panigrahi |
| author_sort | Niranjan Nayak |
| collection | DOAJ |
| description | Recently, cases of rhinoorbital mucormycosis in people diagnosed with COVID-19 have been reported from India particularly. Diabetes mellitus though happens to be an independent risk factor both for severe COVID-19 and mucormycosis, administration of steroids is attributed as a precipitating factor for acquiring the comorbid condition. This opportunistic fungal infection is highly angioinvasive in nature because of which, clinical outcome of infection is invariably poor, especially with rhinocerebral or rhinoorbitocerebral variety of mucormycosis. However, effective management depends upon timely and accurate diagnosis and parenteral administration of amphotericin B. At the same time, judicious use of steroids is a key factor. In addition, glycemic control in those who are severely diabetic is strongly advocated. Exenteration of an eyeball may be indicated if cavernous sinus and intracranial spread are anticipated. Therefore, in order to facilitate faster healing and better penetration of antifungal drugs, surgical debridement of the paranasal sinus cavities and removal of dead tissue from the sinuses are recommended. |
| format | Article |
| id | doaj-art-d652471c3d6b4b62bf4cb068d3006bb6 |
| institution | Kabale University |
| issn | 1918-1493 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-d652471c3d6b4b62bf4cb068d3006bb62025-02-03T07:26:17ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932022-01-01202210.1155/2022/8617212COVID-19 and Mucormycosis Coinfection: How Challenging It IsNiranjan Nayak0Erum Khan1Debadatta Panigrahi2Manipal College of Medical SciencesCollege of MedicineCollege of MedicineRecently, cases of rhinoorbital mucormycosis in people diagnosed with COVID-19 have been reported from India particularly. Diabetes mellitus though happens to be an independent risk factor both for severe COVID-19 and mucormycosis, administration of steroids is attributed as a precipitating factor for acquiring the comorbid condition. This opportunistic fungal infection is highly angioinvasive in nature because of which, clinical outcome of infection is invariably poor, especially with rhinocerebral or rhinoorbitocerebral variety of mucormycosis. However, effective management depends upon timely and accurate diagnosis and parenteral administration of amphotericin B. At the same time, judicious use of steroids is a key factor. In addition, glycemic control in those who are severely diabetic is strongly advocated. Exenteration of an eyeball may be indicated if cavernous sinus and intracranial spread are anticipated. Therefore, in order to facilitate faster healing and better penetration of antifungal drugs, surgical debridement of the paranasal sinus cavities and removal of dead tissue from the sinuses are recommended.http://dx.doi.org/10.1155/2022/8617212 |
| spellingShingle | Niranjan Nayak Erum Khan Debadatta Panigrahi COVID-19 and Mucormycosis Coinfection: How Challenging It Is Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | COVID-19 and Mucormycosis Coinfection: How Challenging It Is |
| title_full | COVID-19 and Mucormycosis Coinfection: How Challenging It Is |
| title_fullStr | COVID-19 and Mucormycosis Coinfection: How Challenging It Is |
| title_full_unstemmed | COVID-19 and Mucormycosis Coinfection: How Challenging It Is |
| title_short | COVID-19 and Mucormycosis Coinfection: How Challenging It Is |
| title_sort | covid 19 and mucormycosis coinfection how challenging it is |
| url | http://dx.doi.org/10.1155/2022/8617212 |
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