Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1

Abstract Sudan ebolavirus (SUDV), like Ebola ebolavirus (EBOV), poses a significant threat to global health and security due to its high lethality. However, unlike EBOV, there are no approved vaccines or treatments for SUDV, and its structural interaction with the endosomal receptor NPC1 remains unc...

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Bibliographic Details
Main Authors: Fan Bu, Gang Ye, Hailey Turner-Hubbard, Morgan Herbst, Bin Liu, Fang Li
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07613-y
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