Predict potential pharmacological mechanisms of Ling-gui-Zhu-gan Decoction in treating unstable angina pectoris using liquid chromatography-mass spectrometry and network pharmacology

Predict potential pharmacological mechanisms of Ling-gui-Zhu-gan Decoction in treating unstable angina pectoris using liquid chromatography-mass spectrometry and network pharmacology

IntroductionLing-Gui-Zhu-Gan Decoction (LGZGD), one of the first batches of classical Chinese prescriptions formally recognized by the Chinese government, has a long-standing history of clinical application and significant potential for modern development. However, the chemical composition and conte...

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Bibliographic Details
Main Authors: Xiaopeng Li, Tan Xue, Panpan Zhang, Fengyu Dong, Han Li, Jing Yao, Haiying Huang, Lizhuang Zhang, Ruixin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Chemistry
Subjects:
Ling-Gui-Zhu-Gan Decoction
transfer rate
UHPLC-Q-Orbitrap/MS
unstable angina
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1649538/full
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