Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation
Most infections by genus Bartonella in immunocompromised patients are caused by B. henselae and B. quintana. Unlike immunocompetent hosts who usually develop milder diseases such as cat scratch disease and trench fever, immunocompromised patients, including those living with HIV/AIDS and posttranspl...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2012/612809 |
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| _version_ | 1832558203753201664 |
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| author | Mosepele Mosepele Dana Mazo Jennifer Cohn |
| author_facet | Mosepele Mosepele Dana Mazo Jennifer Cohn |
| author_sort | Mosepele Mosepele |
| collection | DOAJ |
| description | Most infections by genus Bartonella in immunocompromised patients are caused by B. henselae and B. quintana. Unlike immunocompetent hosts who usually develop milder diseases such as cat scratch disease and trench fever, immunocompromised patients, including those living with HIV/AIDS and posttransplant patients, are more likely to develop different and severe life-threatening disease. This paper will discuss Bartonella's manifestations in immunosuppressed patients and will examine Bartonella's interaction with the immune system including its mechanisms of establishing infection and immune escape. Gaps in current understanding of the immunology of Bartonella infection in immunocompromised hosts will be highlighted. |
| format | Article |
| id | doaj-art-d64357ee5e474feda8d333d9c45b9bf3 |
| institution | Kabale University |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-d64357ee5e474feda8d333d9c45b9bf32025-02-03T01:33:06ZengWileyClinical and Developmental Immunology1740-25221740-25302012-01-01201210.1155/2012/612809612809Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and VasoproliferationMosepele Mosepele0Dana Mazo1Jennifer Cohn2Department of Medicine, Hospital of the University of Pennsylvania, 100 Centrex, Philadelphia, PA 19104, USADepartment of Medicine, Hospital of the University of Pennsylvania, 100 Centrex, Philadelphia, PA 19104, USADepartment of Medicine, Hospital of the University of Pennsylvania, 100 Centrex, Philadelphia, PA 19104, USAMost infections by genus Bartonella in immunocompromised patients are caused by B. henselae and B. quintana. Unlike immunocompetent hosts who usually develop milder diseases such as cat scratch disease and trench fever, immunocompromised patients, including those living with HIV/AIDS and posttransplant patients, are more likely to develop different and severe life-threatening disease. This paper will discuss Bartonella's manifestations in immunosuppressed patients and will examine Bartonella's interaction with the immune system including its mechanisms of establishing infection and immune escape. Gaps in current understanding of the immunology of Bartonella infection in immunocompromised hosts will be highlighted.http://dx.doi.org/10.1155/2012/612809 |
| spellingShingle | Mosepele Mosepele Dana Mazo Jennifer Cohn Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation Clinical and Developmental Immunology |
| title | Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation |
| title_full | Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation |
| title_fullStr | Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation |
| title_full_unstemmed | Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation |
| title_short | Bartonella Infection in Immunocompromised Hosts: Immunology of Vascular Infection and Vasoproliferation |
| title_sort | bartonella infection in immunocompromised hosts immunology of vascular infection and vasoproliferation |
| url | http://dx.doi.org/10.1155/2012/612809 |
| work_keys_str_mv | AT mosepelemosepele bartonellainfectioninimmunocompromisedhostsimmunologyofvascularinfectionandvasoproliferation AT danamazo bartonellainfectioninimmunocompromisedhostsimmunologyofvascularinfectionandvasoproliferation AT jennifercohn bartonellainfectioninimmunocompromisedhostsimmunologyofvascularinfectionandvasoproliferation |