Enhanced Tolerance to Antifungals as a General Feature of Rho<sup>−</sup> Mutants in Yeast Species: Implications to Positive Selection of Respiratory Deficiency
Although the mitochondrial genome is an attribute of all eukaryotes, some yeast species (called petite-positive) can replicate without mitochondrial DNA (mtDNA). Strains without mtDNA (known as rho<sup>−</sup> mutants or petite mutants) are respiration-deficient and require fermentable c...
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Main Authors: | Zachary Johnson, Farhan Nadim, Mikhajlo K. Zubko |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-01-01
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Series: | Microorganisms |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-2607/13/1/99 |
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