Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair

Locally administered liposomal drug depot enhances rheumatoid arthritis treatment by inhibiting inflammation and promoting cartilage repair

Abstract Rheumatoid arthritis (RA) is a chronic autoimmune condition characterized by synovial hyperplasia, where inflammatory macrophages within the joint synovium produce multiple inflammatory cytokines, leading to cartilage damage. The development of therapeutic strategies that combine anti-infla...

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Bibliographic Details
Main Authors: Zongquan Zhang, Guan Wang, Zhuo Zhang, Xiaoya Liang, Guoshuang Wang, Maochang Xu, Xi Yang, Xiaolin Zhong, Chunhong Li, Meiling Zhou
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Nanobiotechnology
Subjects:
Liposomal drug depot
Local joint cavity injection
Rheumatoid arthritis
Inhibiting inflammation
Promoting cartilage repair
Online Access:https://doi.org/10.1186/s12951-025-03110-w
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