Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature
Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor, with a limited number of published reports. Less than three hundred cases have been reported in the literature and only 18 of these cases have been reported in minor palatal salivary glands, though publication...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2019/7416302 |
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| _version_ | 1832553974324002816 |
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| author | Christian Boliere James Murphy Mohammed Qaisi Frances Manosca Henry Fung |
| author_facet | Christian Boliere James Murphy Mohammed Qaisi Frances Manosca Henry Fung |
| author_sort | Christian Boliere |
| collection | DOAJ |
| description | Mammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor, with a limited number of published reports. Less than three hundred cases have been reported in the literature and only 18 of these cases have been reported in minor palatal salivary glands, though publication bias is likely a factor. We present a case of a 57-year-old male who was diagnosed with MASC tumor presenting in a minor salivary gland and briefly review the current literature. MASC has a variety of histological features and different range of clinical behaviors. The histopathological diagnosis of MASC can be difficult, and the immunohistochemical profile of MASC is still being updated. The gold standard for MASC diagnosis is cytogenetics, with the majority having a translocation t(12;15)(p133;q25). Presently, there is no conclusive evidence that MASC should be treated differently than any other low-grade malignant salivary gland tumors, though high-grade transformation has been described. |
| format | Article |
| id | doaj-art-d62bba63bc134fa491687e4e002a0d60 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-d62bba63bc134fa491687e4e002a0d602025-02-03T05:52:44ZengWileyCase Reports in Dentistry2090-64472090-64552019-01-01201910.1155/2019/74163027416302Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the LiteratureChristian Boliere0James Murphy1Mohammed Qaisi2Frances Manosca3Henry Fung4Division of Oral & Maxillofacial Surgery, John H. Stroger Hospital of Cook County, Chicago, IL, USADivision of Oral & Maxillofacial Surgery, John H. Stroger Hospital of Cook County, Chicago, IL, USADivision of Oral & Maxillofacial Surgery, John H. Stroger Hospital of Cook County, Chicago, IL, USADepartment of Pathology, John H. Stroger Hospital of Cook County, Chicago, IL, USADivision of Oral & Maxillofacial Surgery, John H. Stroger Hospital of Cook County, Chicago, IL, USAMammary analogue secretory carcinoma (MASC) is a recently described salivary gland tumor, with a limited number of published reports. Less than three hundred cases have been reported in the literature and only 18 of these cases have been reported in minor palatal salivary glands, though publication bias is likely a factor. We present a case of a 57-year-old male who was diagnosed with MASC tumor presenting in a minor salivary gland and briefly review the current literature. MASC has a variety of histological features and different range of clinical behaviors. The histopathological diagnosis of MASC can be difficult, and the immunohistochemical profile of MASC is still being updated. The gold standard for MASC diagnosis is cytogenetics, with the majority having a translocation t(12;15)(p133;q25). Presently, there is no conclusive evidence that MASC should be treated differently than any other low-grade malignant salivary gland tumors, though high-grade transformation has been described.http://dx.doi.org/10.1155/2019/7416302 |
| spellingShingle | Christian Boliere James Murphy Mohammed Qaisi Frances Manosca Henry Fung Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature Case Reports in Dentistry |
| title | Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature |
| title_full | Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature |
| title_fullStr | Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature |
| title_full_unstemmed | Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature |
| title_short | Mammary Analogue Secretory Carcinoma of the Palate: Case Report and Review of the Literature |
| title_sort | mammary analogue secretory carcinoma of the palate case report and review of the literature |
| url | http://dx.doi.org/10.1155/2019/7416302 |
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