Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy

Background. Maternal risks of betamethasone have been rarely reported. Case. At 36 weeks’ gestation, a previously healthy 23-year-old gravida with fetal intrauterine growth restriction was admitted to the hospital for steroid administration. Twenty-six hours after the first dose of betamethasone, a...

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Main Authors: Mojirayo A. Sarumi, James W. Hole, Robert B. Gherman
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2019/6873057
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author Mojirayo A. Sarumi
James W. Hole
Robert B. Gherman
author_facet Mojirayo A. Sarumi
James W. Hole
Robert B. Gherman
author_sort Mojirayo A. Sarumi
collection DOAJ
description Background. Maternal risks of betamethasone have been rarely reported. Case. At 36 weeks’ gestation, a previously healthy 23-year-old gravida with fetal intrauterine growth restriction was admitted to the hospital for steroid administration. Twenty-six hours after the first dose of betamethasone, a maternal bradycardia was initially noted and eventually nadired at 41 beats per minute. Consultation with the cardio-electrophysiology service revealed no other apparent etiologies for the sinus bradycardia. Due to the asymptomatic nature of the maternal bradycardia, pharmacologic interventions were not recommended. With observation alone, a normal maternal heart rate returned by forty-nine hours after the original betamethasone injection. The patient subsequently had an uneventful intrapartum course. Conclusion. Maternal bradycardia can be associated with antenatal betamethasone administration. Due to the transient nature of this side effect, expectant management is recommended as the treatment option for asymptomatic patients.
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-d6286395931b4c87803cf50e568adbc42025-02-03T01:03:12ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922019-01-01201910.1155/2019/68730576873057Maternal Bradycardia Associated with Betamethasone Administration During PregnancyMojirayo A. Sarumi0James W. Hole1Robert B. Gherman2Division of Maternal-Fetal Medicine, WellSpan Health, York, PA, USADivision of Maternal-Fetal Medicine, WellSpan Health, York, PA, USADivision of Maternal-Fetal Medicine, WellSpan Health, York, PA, USABackground. Maternal risks of betamethasone have been rarely reported. Case. At 36 weeks’ gestation, a previously healthy 23-year-old gravida with fetal intrauterine growth restriction was admitted to the hospital for steroid administration. Twenty-six hours after the first dose of betamethasone, a maternal bradycardia was initially noted and eventually nadired at 41 beats per minute. Consultation with the cardio-electrophysiology service revealed no other apparent etiologies for the sinus bradycardia. Due to the asymptomatic nature of the maternal bradycardia, pharmacologic interventions were not recommended. With observation alone, a normal maternal heart rate returned by forty-nine hours after the original betamethasone injection. The patient subsequently had an uneventful intrapartum course. Conclusion. Maternal bradycardia can be associated with antenatal betamethasone administration. Due to the transient nature of this side effect, expectant management is recommended as the treatment option for asymptomatic patients.http://dx.doi.org/10.1155/2019/6873057
spellingShingle Mojirayo A. Sarumi
James W. Hole
Robert B. Gherman
Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy
Case Reports in Obstetrics and Gynecology
title Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy
title_full Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy
title_fullStr Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy
title_full_unstemmed Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy
title_short Maternal Bradycardia Associated with Betamethasone Administration During Pregnancy
title_sort maternal bradycardia associated with betamethasone administration during pregnancy
url http://dx.doi.org/10.1155/2019/6873057
work_keys_str_mv AT mojirayoasarumi maternalbradycardiaassociatedwithbetamethasoneadministrationduringpregnancy
AT jameswhole maternalbradycardiaassociatedwithbetamethasoneadministrationduringpregnancy
AT robertbgherman maternalbradycardiaassociatedwithbetamethasoneadministrationduringpregnancy