Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease

Introduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disea...

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Main Authors: Nikolić Emilija, Nikolić Aleksandar, Stević Ruža, Brandmajer Tijana, Mićanović Veselin, Mašnić Jelena
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2018/6450962
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author Nikolić Emilija
Nikolić Aleksandar
Stević Ruža
Brandmajer Tijana
Mićanović Veselin
Mašnić Jelena
author_facet Nikolić Emilija
Nikolić Aleksandar
Stević Ruža
Brandmajer Tijana
Mićanović Veselin
Mašnić Jelena
author_sort Nikolić Emilija
collection DOAJ
description Introduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). Aim. We examined the reliability and validity of a modified questionnaire (MQ) to create a model for assessing the health-related quality of life (HRQOL) in COPD. Method. In total, 132 COPD patients completed the MQ. Lung function, smoking index, and exacerbation frequency were measured. Cronbach’s α coefficient of correlation, standard deviation, and multifactorial nonlinear regression analysis were used to verify the internal validity of the MQ and to develop the mathematical model. Results. Female (63) patients had lesser airway obstruction than, and exacerbation frequency similar to that of, male patients. Exacerbation frequency significantly correlated with spirometry parameters in female patients. The MQ total score achieved high internal consistency (Cronbach’s α = 0.89) and showed significant correlations with exacerbation frequency, smoking habit, and spirometry parameters in male patients (p<0.005). Conclusion. The HRQOL questionnaire was shown to be a good indicator of the health status of COPD patients. The mathematical model easily and precisely confirmed the score of HRQOL questionnaire.
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spelling doaj-art-d6092084b14d45b690b06516ac39f5032025-02-03T01:28:12ZengWileyCanadian Respiratory Journal1198-22411916-72452018-01-01201810.1155/2018/64509626450962Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary DiseaseNikolić Emilija0Nikolić Aleksandar1Stević Ruža2Brandmajer Tijana3Mićanović Veselin4Mašnić Jelena5Faculty of Medicine, University of Montenegro, 81000 Podgorica, MontenegroD.o.o. “NCG Inzinjering”, 81000 Podgorica, MontenegroFaculty of Medicine, University of Belgarde, 11000 Belgrade, SerbiaFaculty of Medicine, University of Montenegro, 81000 Podgorica, MontenegroFaculty of Philosophy, University of Montenegro, 81000 Podgorica, MontenegroFaculty of Philosophy, University of Montenegro, 81000 Podgorica, MontenegroIntroduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). Aim. We examined the reliability and validity of a modified questionnaire (MQ) to create a model for assessing the health-related quality of life (HRQOL) in COPD. Method. In total, 132 COPD patients completed the MQ. Lung function, smoking index, and exacerbation frequency were measured. Cronbach’s α coefficient of correlation, standard deviation, and multifactorial nonlinear regression analysis were used to verify the internal validity of the MQ and to develop the mathematical model. Results. Female (63) patients had lesser airway obstruction than, and exacerbation frequency similar to that of, male patients. Exacerbation frequency significantly correlated with spirometry parameters in female patients. The MQ total score achieved high internal consistency (Cronbach’s α = 0.89) and showed significant correlations with exacerbation frequency, smoking habit, and spirometry parameters in male patients (p<0.005). Conclusion. The HRQOL questionnaire was shown to be a good indicator of the health status of COPD patients. The mathematical model easily and precisely confirmed the score of HRQOL questionnaire.http://dx.doi.org/10.1155/2018/6450962
spellingShingle Nikolić Emilija
Nikolić Aleksandar
Stević Ruža
Brandmajer Tijana
Mićanović Veselin
Mašnić Jelena
Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
Canadian Respiratory Journal
title Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
title_full Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
title_fullStr Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
title_full_unstemmed Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
title_short Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
title_sort model for developing a health related quality of life questionnaire for chronic obstructive pulmonary disease
url http://dx.doi.org/10.1155/2018/6450962
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