Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease
Introduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disea...
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Format: | Article |
Language: | English |
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Wiley
2018-01-01
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Series: | Canadian Respiratory Journal |
Online Access: | http://dx.doi.org/10.1155/2018/6450962 |
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author | Nikolić Emilija Nikolić Aleksandar Stević Ruža Brandmajer Tijana Mićanović Veselin Mašnić Jelena |
author_facet | Nikolić Emilija Nikolić Aleksandar Stević Ruža Brandmajer Tijana Mićanović Veselin Mašnić Jelena |
author_sort | Nikolić Emilija |
collection | DOAJ |
description | Introduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). Aim. We examined the reliability and validity of a modified questionnaire (MQ) to create a model for assessing the health-related quality of life (HRQOL) in COPD. Method. In total, 132 COPD patients completed the MQ. Lung function, smoking index, and exacerbation frequency were measured. Cronbach’s α coefficient of correlation, standard deviation, and multifactorial nonlinear regression analysis were used to verify the internal validity of the MQ and to develop the mathematical model. Results. Female (63) patients had lesser airway obstruction than, and exacerbation frequency similar to that of, male patients. Exacerbation frequency significantly correlated with spirometry parameters in female patients. The MQ total score achieved high internal consistency (Cronbach’s α = 0.89) and showed significant correlations with exacerbation frequency, smoking habit, and spirometry parameters in male patients (p<0.005). Conclusion. The HRQOL questionnaire was shown to be a good indicator of the health status of COPD patients. The mathematical model easily and precisely confirmed the score of HRQOL questionnaire. |
format | Article |
id | doaj-art-d6092084b14d45b690b06516ac39f503 |
institution | Kabale University |
issn | 1198-2241 1916-7245 |
language | English |
publishDate | 2018-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Respiratory Journal |
spelling | doaj-art-d6092084b14d45b690b06516ac39f5032025-02-03T01:28:12ZengWileyCanadian Respiratory Journal1198-22411916-72452018-01-01201810.1155/2018/64509626450962Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary DiseaseNikolić Emilija0Nikolić Aleksandar1Stević Ruža2Brandmajer Tijana3Mićanović Veselin4Mašnić Jelena5Faculty of Medicine, University of Montenegro, 81000 Podgorica, MontenegroD.o.o. “NCG Inzinjering”, 81000 Podgorica, MontenegroFaculty of Medicine, University of Belgarde, 11000 Belgrade, SerbiaFaculty of Medicine, University of Montenegro, 81000 Podgorica, MontenegroFaculty of Philosophy, University of Montenegro, 81000 Podgorica, MontenegroFaculty of Philosophy, University of Montenegro, 81000 Podgorica, MontenegroIntroduction. The St. George’s Respiratory Questionnaire (SGRQ), Modified Medical Research Council (mMRC) Dyspnea Scale, Hospital Anxiety and Depression Scale (HADS), and general health questionnaire (SF-36) are widely used for chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD). Aim. We examined the reliability and validity of a modified questionnaire (MQ) to create a model for assessing the health-related quality of life (HRQOL) in COPD. Method. In total, 132 COPD patients completed the MQ. Lung function, smoking index, and exacerbation frequency were measured. Cronbach’s α coefficient of correlation, standard deviation, and multifactorial nonlinear regression analysis were used to verify the internal validity of the MQ and to develop the mathematical model. Results. Female (63) patients had lesser airway obstruction than, and exacerbation frequency similar to that of, male patients. Exacerbation frequency significantly correlated with spirometry parameters in female patients. The MQ total score achieved high internal consistency (Cronbach’s α = 0.89) and showed significant correlations with exacerbation frequency, smoking habit, and spirometry parameters in male patients (p<0.005). Conclusion. The HRQOL questionnaire was shown to be a good indicator of the health status of COPD patients. The mathematical model easily and precisely confirmed the score of HRQOL questionnaire.http://dx.doi.org/10.1155/2018/6450962 |
spellingShingle | Nikolić Emilija Nikolić Aleksandar Stević Ruža Brandmajer Tijana Mićanović Veselin Mašnić Jelena Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease Canadian Respiratory Journal |
title | Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease |
title_full | Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease |
title_fullStr | Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease |
title_full_unstemmed | Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease |
title_short | Model for Developing a Health-Related Quality of Life Questionnaire for Chronic Obstructive Pulmonary Disease |
title_sort | model for developing a health related quality of life questionnaire for chronic obstructive pulmonary disease |
url | http://dx.doi.org/10.1155/2018/6450962 |
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