In Vitro and In Vivo Improvement of Islet Quality and Transplantation Successes following Islet Treatment with Biomaterials in Diabetic Rats
Background. Loss of islet survival and function, caused by native niche disruption and oxidative stress induction during mechanical and enzymatic isolation, limits the effectiveness of islet transplantation. Reconstitution of islet microenvironment, vascularization, and decreased oxidative stress wi...
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Main Authors: | Marzieh Nemati, Zahra Ebrahimi, Narges Karbalaei, Sanaz Dastghaib, Sara Khakshournia, Mojtaba Sargazi |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
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Series: | Journal of Diabetes Research |
Online Access: | http://dx.doi.org/10.1155/2023/1399917 |
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