NPF signaling-dependent maintenance of metabolic homeostasis in the pea aphid is mediated by a highly selective ligand-receptor interaction and tissue-specific changes in NPF and NPFR

NPF signaling-dependent maintenance of metabolic homeostasis in the pea aphid is mediated by a highly selective ligand-receptor interaction and tissue-specific changes in NPF and NPFR

Neuropeptide F (NPF) and its receptor (NPFR) are important regulators of food intake, physiology and metabolism in insects. Focusing on a major crop pest, the pea aphid Acyrthosiphon pisum, it is shown that the predicted NPFR is a highly selective NPF receptor. Its activation by NPFs from other inse...

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Bibliographic Details
Main Authors: Cissy Huygens, Mélanie Ribeiro Lopes, El-Sayed Baz, Jozef Vanden Broeck, Federica Calevro, Patrick Callaerts
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Heliyon
Subjects:
Neuropeptide F
Acyrthosiphon pisum
Metabolic homeostasis
Insect physiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025018900
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