SFRP2 mediates Epstein-Barr virus and bladder cancer risk: a Mendelian randomization study and colocalization analysis

SFRP2 mediates Epstein-Barr virus and bladder cancer risk: a Mendelian randomization study and colocalization analysis

Abstract Studies suggest a possible association between Epstein-Barr virus (EBV) infection and bladder cancer (BCa) risk, though this remains unclear. Secreted frizzled-related protein (sFRP) is also linked to BCa, with some DNA viruses potentially regulating its expression. This study used Mendelia...

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Bibliographic Details
Main Authors: Jian Li, Bing Yang, Lei Guo, Wenqi Huang, Qiong Hu, Hongting Yan, Changpu Du, Rong Tan, Dongxin Tang
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Epstein-Barr virus
Bladder cancer
Secreted frizzled-related protein
Causal association
Mendelian randomization
Online Access:https://doi.org/10.1038/s41598-025-91594-9
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https://doi.org/10.1038/s41598-025-91594-9

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