Autoimmune pancreatitis type 1 and type 2: A report of two cases
Introduction. Autoimmune pancreatitis is a disease associated with autoimmune mechanisms, clinically manifested mostly as obstructive icterus with or with no entire or partial enlargement of the pancreas, histological lymphoplas-mocytic infiltration, fibrosis or granulocytic epithelial lesions with...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2017-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600192B.pdf |
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| author | Brčerević Irina Doder Radoje Perišić Nenad Petrović Stanko Jović Jasna Hristović Dejan Đorđević Zoran Tasić-Radić Olga |
| author_facet | Brčerević Irina Doder Radoje Perišić Nenad Petrović Stanko Jović Jasna Hristović Dejan Đorđević Zoran Tasić-Radić Olga |
| author_sort | Brčerević Irina |
| collection | DOAJ |
| description | Introduction. Autoimmune pancreatitis is a disease associated with autoimmune mechanisms, clinically manifested mostly as obstructive icterus with or with no entire or partial enlargement of the pancreas, histological lymphoplas-mocytic infiltration, fibrosis or granulocytic epithelial lesions with a favourable therapeutic response to the application of corticosteroids. Type 1 autoimmune pancreatitis is a systemic disease befalling the group of IgG4-related diseases in contrast to type 2 which is specific for pancreas disease. Case report. We presented two cases. The first one was a 64-year-old male patient with autoimmune pancreatitis complaining of abdominal pain, weight loss, weakness and exhaustion. Clinical examination showed a rare IgG4 autoimmune pancreatitis. The second one was a 37-year-old male patient complaining of abdominal pain with diarrhea. The diagnosis made revealed the presence of type 2 autoimmune pancreatitis. Following the diagnosis, immunosuppressive therapy was administered to both patients leading to the improvement of their general condition. Conclusion. Autoimmune pancreatitis is a rare disease, sometimes not easy to differ from pancreatic tumor or bile duct tumor with poor prognosis. Thus, early recognition of the disease is very important, since adequate treatment significantly increases the course and the outcomes of the disease. |
| format | Article |
| id | doaj-art-d5a9d9d9c010416d885d7c3bcdc0bbd5 |
| institution | DOAJ |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-d5a9d9d9c010416d885d7c3bcdc0bbd52025-08-20T03:06:05ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202017-01-0174436136610.2298/VSP151007192B0042-84501600192BAutoimmune pancreatitis type 1 and type 2: A report of two casesBrčerević Irina0Doder Radoje1Perišić Nenad2Petrović Stanko3Jović Jasna4Hristović Dejan5Đorđević Zoran6Tasić-Radić Olga7Military Medical Academy, Clinic for Gastroenterology and Hepathology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic for Gastroenterology and Hepathology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic for Gastroenterology and Hepathology, BelgradeMilitary Medical Academy, Clinic for Gastroenterology and Hepathology, BelgradeMilitary Medical Academy, Clinic for Gastroenterology and Hepathology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic for Infectious and Tropical Diseases, BelgradeMilitary Medical Academy, Institute of Radiology, BelgradeMilitary Medical Academy, Institute of Pathology, BelgradeIntroduction. Autoimmune pancreatitis is a disease associated with autoimmune mechanisms, clinically manifested mostly as obstructive icterus with or with no entire or partial enlargement of the pancreas, histological lymphoplas-mocytic infiltration, fibrosis or granulocytic epithelial lesions with a favourable therapeutic response to the application of corticosteroids. Type 1 autoimmune pancreatitis is a systemic disease befalling the group of IgG4-related diseases in contrast to type 2 which is specific for pancreas disease. Case report. We presented two cases. The first one was a 64-year-old male patient with autoimmune pancreatitis complaining of abdominal pain, weight loss, weakness and exhaustion. Clinical examination showed a rare IgG4 autoimmune pancreatitis. The second one was a 37-year-old male patient complaining of abdominal pain with diarrhea. The diagnosis made revealed the presence of type 2 autoimmune pancreatitis. Following the diagnosis, immunosuppressive therapy was administered to both patients leading to the improvement of their general condition. Conclusion. Autoimmune pancreatitis is a rare disease, sometimes not easy to differ from pancreatic tumor or bile duct tumor with poor prognosis. Thus, early recognition of the disease is very important, since adequate treatment significantly increases the course and the outcomes of the disease.http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600192B.pdfpancreatitisautoimmune diseasesdiagnostic techniques and proceduresdiagnosis, differentialdrug therapy |
| spellingShingle | Brčerević Irina Doder Radoje Perišić Nenad Petrović Stanko Jović Jasna Hristović Dejan Đorđević Zoran Tasić-Radić Olga Autoimmune pancreatitis type 1 and type 2: A report of two cases Vojnosanitetski Pregled pancreatitis autoimmune diseases diagnostic techniques and procedures diagnosis, differential drug therapy |
| title | Autoimmune pancreatitis type 1 and type 2: A report of two cases |
| title_full | Autoimmune pancreatitis type 1 and type 2: A report of two cases |
| title_fullStr | Autoimmune pancreatitis type 1 and type 2: A report of two cases |
| title_full_unstemmed | Autoimmune pancreatitis type 1 and type 2: A report of two cases |
| title_short | Autoimmune pancreatitis type 1 and type 2: A report of two cases |
| title_sort | autoimmune pancreatitis type 1 and type 2 a report of two cases |
| topic | pancreatitis autoimmune diseases diagnostic techniques and procedures diagnosis, differential drug therapy |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2017/0042-84501600192B.pdf |
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