C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis
Conclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the s...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2024/1386147 |
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| _version_ | 1832569153449361408 |
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| author | Zhong-Bo Ge Xin-Yun Zhang Chun-Miao Zhang Tao-Tao Xu Si-Yi Li Meng-Xiao Wei Xin-Yuan Ding Cai-Juan Bai Han Wang Hai-Hong Zhou Ming-Yu Wang |
| author_facet | Zhong-Bo Ge Xin-Yun Zhang Chun-Miao Zhang Tao-Tao Xu Si-Yi Li Meng-Xiao Wei Xin-Yuan Ding Cai-Juan Bai Han Wang Hai-Hong Zhou Ming-Yu Wang |
| author_sort | Zhong-Bo Ge |
| collection | DOAJ |
| description | Conclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the significant limitations associated with the use of mouse models. |
| format | Article |
| id | doaj-art-d5a9679cd9624b0c8687adadc9f88716 |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-d5a9679cd9624b0c8687adadc9f887162025-02-02T23:07:55ZengWileyGastroenterology Research and Practice1687-630X2024-01-01202410.1155/2024/1386147C-Reactive Protein Is Not the Driver Factor in Ulcerative ColitisZhong-Bo Ge0Xin-Yun Zhang1Chun-Miao Zhang2Tao-Tao Xu3Si-Yi Li4Meng-Xiao Wei5Xin-Yuan Ding6Cai-Juan Bai7Han Wang8Hai-Hong Zhou9Ming-Yu Wang10MOE Key Laboratory of Cell Activities and Stress AdaptationsMOE Key Laboratory of Cell Activities and Stress AdaptationsMOE Key Laboratory of Cell Activities and Stress AdaptationsMOE Key Laboratory of Cell Activities and Stress AdaptationsMOE Key Laboratory of Cell Activities and Stress AdaptationsMOE Key Laboratory of Cell Activities and Stress AdaptationsMOE Key Laboratory of Cell Activities and Stress AdaptationsNHC Key Laboratory of Diagnosis and Therapy of Gastrointestinal TumourDepartment of Blood TransfusionTranslational Medicine Research CentreMOE Key Laboratory of Cell Activities and Stress AdaptationsConclusion: The results of our study suggest that CRP may not directly mediate ulcerative colitis. Instead, it is more likely to be a bystander that is present alongside with elevated inflammatory factors. Further investigation is warranted to determine the precise role of CRP in humans, given the significant limitations associated with the use of mouse models.http://dx.doi.org/10.1155/2024/1386147 |
| spellingShingle | Zhong-Bo Ge Xin-Yun Zhang Chun-Miao Zhang Tao-Tao Xu Si-Yi Li Meng-Xiao Wei Xin-Yuan Ding Cai-Juan Bai Han Wang Hai-Hong Zhou Ming-Yu Wang C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis Gastroenterology Research and Practice |
| title | C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis |
| title_full | C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis |
| title_fullStr | C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis |
| title_full_unstemmed | C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis |
| title_short | C-Reactive Protein Is Not the Driver Factor in Ulcerative Colitis |
| title_sort | c reactive protein is not the driver factor in ulcerative colitis |
| url | http://dx.doi.org/10.1155/2024/1386147 |
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