Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives
Synthesis of some biologically active benzothiazolotriazine derivatives by microwave irradiation is reported. 2-Amino-6-substituted benzothiazoles 1 on treatment with benzaldehyde in anhydrous ethanol afforded 2-benzylidenoimino-6-substitutedbenzothiazoles 2 which underwent cyclisation with ammonium...
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2006/486723 |
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| author | Prashant Kriplani Pawan Swarnkar Rinku Maheshwari K. G. Ojha |
| author_facet | Prashant Kriplani Pawan Swarnkar Rinku Maheshwari K. G. Ojha |
| author_sort | Prashant Kriplani |
| collection | DOAJ |
| description | Synthesis of some biologically active benzothiazolotriazine derivatives by microwave irradiation is reported. 2-Amino-6-substituted benzothiazoles 1 on treatment with benzaldehyde in anhydrous ethanol afforded 2-benzylidenoimino-6-substitutedbenzothiazoles 2 which underwent cyclisation with ammoniumthiocyanate in dioxane to give 2-phenyl benzothiazolo [3,2-α]-s-triazine-4-[3H] thiones 3.These both steps were carried out in microwave. Compound 3 with benzoyl chloride in anhydrous pyridine gave 2-phenyl-3-(benzoyl) benzothiazolo [3,2-α]-s-triazine-4-thiones 4 in good yields. The structure of all these compounds have been supported by their elemental analysis and their spectral data. All synthesized compounds were tested for their antibacterial activity using standard drug. |
| format | Article |
| id | doaj-art-d58212df65dc47b4baadfd9462570d32 |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-d58212df65dc47b4baadfd9462570d322025-02-03T01:12:17ZengWileyE-Journal of Chemistry0973-49452090-98102006-01-013430731210.1155/2006/486723Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine DerivativesPrashant Kriplani0Pawan Swarnkar1Rinku Maheshwari2K. G. Ojha3Department of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaDepartment of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaDepartment of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaDepartment of Pure and Applied Chemistry, M. D. S. University, Ajmer-305 009, IndiaSynthesis of some biologically active benzothiazolotriazine derivatives by microwave irradiation is reported. 2-Amino-6-substituted benzothiazoles 1 on treatment with benzaldehyde in anhydrous ethanol afforded 2-benzylidenoimino-6-substitutedbenzothiazoles 2 which underwent cyclisation with ammoniumthiocyanate in dioxane to give 2-phenyl benzothiazolo [3,2-α]-s-triazine-4-[3H] thiones 3.These both steps were carried out in microwave. Compound 3 with benzoyl chloride in anhydrous pyridine gave 2-phenyl-3-(benzoyl) benzothiazolo [3,2-α]-s-triazine-4-thiones 4 in good yields. The structure of all these compounds have been supported by their elemental analysis and their spectral data. All synthesized compounds were tested for their antibacterial activity using standard drug.http://dx.doi.org/10.1155/2006/486723 |
| spellingShingle | Prashant Kriplani Pawan Swarnkar Rinku Maheshwari K. G. Ojha Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives E-Journal of Chemistry |
| title | Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives |
| title_full | Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives |
| title_fullStr | Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives |
| title_full_unstemmed | Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives |
| title_short | Microwave Assisted Synthesis of Some Biologically Active Benzothiazolotriazine Derivatives |
| title_sort | microwave assisted synthesis of some biologically active benzothiazolotriazine derivatives |
| url | http://dx.doi.org/10.1155/2006/486723 |
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