Oxaliplatin-Loaded Chitosan Nanoparticles Decorated with Cetuximab Single-Chain Variable Fragment for Human Colorectal Cancer Treatment

Oxaliplatin-Loaded Chitosan Nanoparticles Decorated with Cetuximab Single-Chain Variable Fragment for Human Colorectal Cancer Treatment

Objective: Colorectal cancer (CRC) is the second leading cause of cancer-related deaths worldwide. Engineeredbiomolecules can be used as a targeted tool to deliver drugs directly to tumors that reduce the adverse effects of conventionaltreatments. We aimed to prepare non-targeted oxaliplatin-loaded...

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Bibliographic Details
Main Authors: Khadijeh Falahzadeh, Fariba Esmaeili, Leila Nematollahi, Elham Bayat, Mehdi Khoobi, Mohammadali Mazloomi, Masumeh Jalalvand, Reza Faridi Majidi, Babak Negahdari
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2024-09-01
Series:Cell Journal
Subjects:
cetuximab
chitosan
colorectal cancer
drug delivery systems
oxaliplatin
Online Access:https://www.celljournal.org/article_718311_75fe512d40213af54f76cbf55fb1b980.pdf
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