A minimal mathematical model for the initial molecular interactions of death receptor signalling

Tumor necrosis factor (TNF) is the name giving member of a large cytokine family mirrored by a respective cell membrane receptor super family. TNF itself is a strong proinflammatory regulator of the innate immune system, but has been also recognized as a major factor in progression of autoimmune dis...

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Bibliographic Details
Main Authors: Christian Winkel, Simon Neumann, Christina Surulescu, Peter Scheurich
Format: Article
Language:English
Published: AIMS Press 2012-06-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2012.9.663
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